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| 摘要: |
| 目的:探讨中医治疗子宫内膜异位症的作用机理.方法:以手术移植法制作大鼠子宫内膜异位症模型.分为4组:妇痛宁治疗组、正常对照组、模型对照组及痛经丸对照组.检测各组大鼠垂体、下丘脑、异位内膜组织中β-内啡肽、强啡肽;血清中内皮素-1等含量的变化.结果:妇痛宁治疗组明显高于其他组.结论:中药妇痛宁可通过神经内分泌整体调节作用,达到治疗子宫内膜异位症的目的. |
| 关键词: 活血化瘀 软坚散结 子宫内膜异位症 神经内分泌 |
| DOI：10.11656/j.issn.1672-1519.2002.01.33 |
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| 基金项目: |
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| Experimental Research on the Neuroendorine Influence in Treating Endometriosis(EMT) by the Therapy of Promoting Blood Circulation to Dispel Blood Stasis, Softening and Resolving Hard Masses(Fu Tong Ning) |
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Xu Lifen
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| Abstract: |
| Objective:To study the mechanism of modulation on treating endometriosis(EMT).Method:Experimental EMT rat models were made by surgical transplantation. All rats were randomly divided into 4 groups:FuTongNing treating group,normal control group,model control group and TongJingWan control group. The following indexes were examined:the level of β-endothelin(β-EP) and dynorphin(DynA-13) in rat’s pituitary,thalamencephalon and ectopic endometrium,the level of endothelin(ET-1) in serum.Results:The indexes of FuTongNing treating group were higher than other groups obviously.Conclusion:FuTongNing plays a role of integral modulation on treating EMT by taking effect on neuroendorine system. |
| Key words: Promoting blood circulation to dispel blood stasis Softening and resolving hard masses Endometriosis Neurosecretion |
