灯盏花注射液治疗冠心病的临床观察

Clinical Observation of Dengzhanhua Injection on Coronary Heart Disease

关键词:  灯盏花注射液  冠心病  血液流变学  心电图

Key words:  Dengzhanhua Injection  Coronary heart disease  Blood rheology  ECG

摘要:

目的:观察灯盏花注射液治疗冠心病的临床疗效。方法:对60例冠心病患者,随机单盲分为治疗组30例,采用常规口服扩冠药加灯盏花注射液治疗;对照组30例,单用常规口服扩冠药。结果:治疗组、对照组治疗冠心病的总有效率分别为83.3%、53.3%,两组比较差异有显着性(P<0.05);2组均可使超氧化物歧化酶(SOD)明显升高,脂质过氧化物(LPO)明显降低,且两组比较差异有显着性(P<0.05);2组心电图的总有效率分别为80.0%,53.3%,两组比较差异有显着性(P<0.05);2组对血液流变学的影响的总有效率分别为86.7%、63.3%,两组比较差异有显着性(P<0.05)。结论:加用灯盏花注射液治疗冠心病比单用常规口服扩冠药疗效更好。

Abstract:

Objective: To observe the clinical effect of Dengzhanhua Injection for treating coronary heart disease. Methods: Sixty patients were randomly and blindly assigned to receive routine oral dilational medicine for coronary artery plus Dengzhanhua Injection in treatment group (n=30) and dilational medicine alone in control group (n=30). Results: The total effective rates in treatment group and control group were 83.3% and 53.3% respectively with significant difference (P<0.05). Both of these two methods could markedly increase SOD and lower LPO in blood. Obvious difference was found between these two groups (P<0.05). For changes of ECG and blood rheology,the effective rates were 80%, 53.3% and 86.7%, 63.3% and the comparison of both parameters between two groups had significant difference (P<0.05). Conclusion: The therapeutic effect of combined use of Dengzhanhua Injection and routine administration of dilational medicine for coronary disease is better than that of the latter alone.