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温通针法减轻脑缺血损伤的实验研究——对脑缺血再灌注大鼠脑组织Ca及Mg元素含量的影响
梁宪如1, 郭永明2, 郑俊江3, 郑俊朋3, 严兴科3
1.武警医学院附属医院, 天津, 300162;2.天津中医学院, 天津, 300193;3.甘肃郑氏针法研究会, 甘肃兰州, 730000
摘要:
目的:观察温通针法治疗脑缺血的作用机理。方法:用改良的四血管结扎法造成大鼠脑缺血及再灌注模型,观察脑组织Ca及Mg元素、脑组织含水量的变化及温通针法的干预效应。结果:脑缺血再灌注后再灌组脑组织Ca元素及含水量显着增高(P<0.01),而Mg元素含量显着降低(P<0.01),用温通针法治疗后脑组织含水量、Ca元素含量明显降低(P<0.01),Mg元素明显升高(P<0.01)。结论:提示该针法具有明显减轻脑水肿,使再灌注脑组织Ca元素含量降低,Mg元素含量升高,从而减轻再灌注损伤的作用。
关键词:  脑缺血再灌注  大鼠  Ca元素  Mg元素  温通针法
DOI:10.11656/j.issn.1672-1519.2002.03.18
分类号:
基金项目:甘肃省科学技术攻关项目(课题号GS992-A43-064)
Influence of Warming-promotion Method of Acupuncture on the Contents of the Elements Ca and Mg in Brain Tissue of Rats with Cerebral Ischemia and Reperfusion
Liang Xianru,Guo Yongming,Zheng Junjiang
The Affiliated Hospital to Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China
Abstract:
Objective: To observe the effects of warming-promotion method of acupuncture on the contents of the elements Ca and Mg in brain tissue of rats with cerebral ischemia and reperfusion (I/R) injury. Methods: The contents of Ca, Mg and water in rats’ brain and the curative effect were observed in experimental model of I/R induced by modified method of 4-vessel ligation. Results: The H2O and Ca content in the brain tissue increased significantly(P<0.01)while the Mg content decreased significantly (P<0.01)when compared with those in control group. After treating with the warming-promotion method of acupuncture, the H2O and Ca content in the brain tissue decreased significantly while the Mg content increased significantly when compared with model group(P<0.01). Conclusion: It suggests that the warming-promoting method of acupuncture can reduce the severity of the injury of cerebral I/R.
Key words:  Cerebral ischemia and reperfusion  Rat  Ca  Mg  Warming-promotion method of acupuncture
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