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温通针法减轻脑缺血损伤的实验研究——对脑缺血再灌注大鼠脑组织Ca及Mg元素含量的影响 |
梁宪如1, 郭永明2, 郑俊江3, 郑俊朋3, 严兴科3
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1.武警医学院附属医院, 天津, 300162;2.天津中医学院, 天津, 300193;3.甘肃郑氏针法研究会, 甘肃兰州, 730000
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摘要: |
目的:观察温通针法治疗脑缺血的作用机理。方法:用改良的四血管结扎法造成大鼠脑缺血及再灌注模型,观察脑组织Ca及Mg元素、脑组织含水量的变化及温通针法的干预效应。结果:脑缺血再灌注后再灌组脑组织Ca元素及含水量显着增高(P<0.01),而Mg元素含量显着降低(P<0.01),用温通针法治疗后脑组织含水量、Ca元素含量明显降低(P<0.01),Mg元素明显升高(P<0.01)。结论:提示该针法具有明显减轻脑水肿,使再灌注脑组织Ca元素含量降低,Mg元素含量升高,从而减轻再灌注损伤的作用。 |
关键词: 脑缺血再灌注 大鼠 Ca元素 Mg元素 温通针法 |
DOI:10.11656/j.issn.1672-1519.2002.03.18 |
分类号: |
基金项目:甘肃省科学技术攻关项目(课题号GS992-A43-064) |
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Influence of Warming-promotion Method of Acupuncture on the Contents of the Elements Ca and Mg in Brain Tissue of Rats with Cerebral Ischemia and Reperfusion |
Liang Xianru,Guo Yongming,Zheng Junjiang
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The Affiliated Hospital to Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China
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Abstract: |
Objective: To observe the effects of warming-promotion method of acupuncture on the contents of the elements Ca and Mg in brain tissue of rats with cerebral ischemia and reperfusion (I/R) injury. Methods: The contents of Ca, Mg and water in rats’ brain and the curative effect were observed in experimental model of I/R induced by modified method of 4-vessel ligation. Results: The H2O and Ca content in the brain tissue increased significantly(P<0.01)while the Mg content decreased significantly (P<0.01)when compared with those in control group. After treating with the warming-promotion method of acupuncture, the H2O and Ca content in the brain tissue decreased significantly while the Mg content increased significantly when compared with model group(P<0.01). Conclusion: It suggests that the warming-promoting method of acupuncture can reduce the severity of the injury of cerebral I/R. |
Key words: Cerebral ischemia and reperfusion Rat Ca Mg Warming-promotion method of acupuncture |