回神丹颗粒剂治疗老年期血管性痴呆的临床研究

Clinical Research of Huichundan Granule on Senile Vascular Dementia (VD)

关键词:  血管性痴呆  回神丹颗粒剂  中医药疗法  临床应用

Key words:  vascular dementia  Huichundan Granule  therapeutics of TCM  clinical application

摘要:

目的: 观察中药制剂回神丹颗粒剂治疗老年期血管性痴呆的临床疗效。方法: 将全部病例分为观察组(n=118),对照组(n=30).观察组服用回神丹颗粒剂,对照组服用西药喜得镇。采用国际通用智力量表(MMSE)评分标准,观察两组患者在时间定向力、空间定向力、语言功能等方面的改善情况。结果: 观察组总有效率为89.83%,对照组为60.00%,对两组有效病例追踪观察6个月,观察组好转维持率为99.06%,恶化率为0.94%;对照组好转维持率为83.33%,恶化率为16.67%.结论: 回神丹治疗血管痴呆疗效可靠且持久。

Abstract:

Objective: To observe the clinical effect of Chinese patent medicine Huichundan Granule on treating senile VD. Methods: All cases were divided into treatment group(n=18, given Huichundan Granule) and control group (n=30, given western medicine Hydergcine).Using MMSG core creterion, the abilities of temporal orientation, space orientation, speech and so on in both groups were observed.Results: The total effective rates were 89.83%, 60.00% in both groups respectively. Six months after that, the sustaining improving rate were 99.06%, 83.33%, the deteriorative rates 0.94%, 16.67% in treatment group and control group respectively.Conclusion: Huichundan Granule has a certain persistent effect on treating senile VD.