| 摘要: |
| [目的]从宏观行为学角度证实情志疾病基本病机—气机失调的客观存在及复方中药的干预作用。[方法]采用多项心理应激结合小剂量链脲佐菌素腹腔注射的复合方式,模拟心理应激诱发实验性2型糖尿病的大鼠模型,借鉴经典的旷场实验方法评定心理应激对2型糖尿病大鼠行为的影响,同时观察了具有理气、降逆散结作用的复方中药心身5号的调节作用。[结果]心理应激可导致实验性2型糖尿病大鼠的行为异常,心身5号可调节异常的行为改变。[结论]心理应激诱发实验性2型糖尿病大鼠行为异常是气机失调的外在宏观表现,反映情志疾病的共同病机气机失调的客观存在,及具有理气降逆散结作用的复方中药心身5号具有明显的调节效应。 |
| 关键词: 心理应激 气机失调 行为学 |
| DOI：10.11656/j.issn.1672-1519.2003.04.40 |
| 分类号: |
| 基金项目:天津市卫生局中医中西医结合科研项目资助(200017) |
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| Behavior change of rats with experimental diabetes 2 induced by psychological stress and Chinese medicine treatment |
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LI Jie,LIU Yan-min,LI Qing-he
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Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| [Objective] To verify the presence of qi disorder of psychosomatic diseases objectively from macroscopic behavior science and to study the interveution of Chinese medicine. [Methods] The rat model with diabetes 2 was induced by various kinds of psychosomatic stress and small dosage STZ. The behavior influence of rats with diabetics 2 was assessed by classic Open Field Test. The regrlation effect of XinshenⅤ, a patent medicine with the function of regulating qi, lowering the reverse, dispeling the hard mass, was observed. [Results] Psychological stress could cause abnormal behavior in rats with diabetics 2. [Conclusion] The abnormal behavior of rats with experimental diabetes 2 induced by psychological stress is the macroscopic appearance of qi disorders and XinshengⅤcan regulate it markedly. |
| Key words: psychological stress qi disorder behavior science |
