针刺对2型糖尿病大鼠胰岛素抵抗影响的实验研究

Effect of Acupuncture on Insulin Resistance in Rats with Type 2 Diabetes

关键词:  2型糖尿病  胰岛素抵抗  针灸疗法

Key words:  type 2 diabetes  insulin resist  acupuncture therapy

摘要:

[目的]探讨针刺对2型糖尿病胰岛素抵抗的作用机制。[方法]采用2型糖尿病(NIDDM)大鼠模型,分为两组,观察组10只,以针刺治疗,取穴:中脘、曲池、合谷、足三里等。对照组10只,不做治疗。[结果]针刺后,2型糖尿病大鼠血糖明显下降,胰岛素敏感指数明显升高,外周组织对葡萄糖的摄取率显著增加。两组相比较,有显著性差异(P<0.01,P<0.05)。[结论]针刺能使2型糖尿病大鼠胰岛素抵抗逆转或减轻。

Abstract:

[Objective] To explore the effective mechanism of acupuncture on insulin resistance in rats with type 2 diabetes. [Methods] Rats with type 2 diabetes were selected and randomly divided into two groups: treatment group (10 rats)with acupuncture therapy,using Zhongwan,Quchi,Hegu,Zusanli etc. as the acupoints; control group (10 rats) without any treatment. [Results] Blood sugar of rats with type 2 diabetes was decreased after acupuncture apparently,and insulin sensitivity index was increased markedly. Intaking rate of glucose in peripheral tissue was enhanced apparently. There was significantly difference between two groups (P<0.01,P< 0.05).[Conclusion] Acupuncture can ameliorate or reverse the insulin resistance of rats with type 2 diabetes.