摘要: |
[目的]观察黄芪穴位注射减少迁延性心肌炎患儿病情波动的效果,探讨其调整机体免疫功能作用。[方法]将迁延性心肌炎患儿按1:1的比例随机分为试验组和对照组,试验组在心肌炎常规方案治疗的基础上,加用黄芪足三里穴位注射,对照组则单用心肌炎常规方案。疗程均为3个月,并随访至少1a,观察治疗前后的免疫功能改善以及随访期病情波动情况。[结果]两组患儿病情波动次数均较疗前明显减少,治疗前后差值比较,差异均有非常显著性意义(P<0.001);组间比较,差异也有显著性意义(P<0.05),试验组低于对照组。两组各项免疫指标比较,疗后T淋巴细胞亚群、自然杀伤(NK)细胞活性、免疫球蛋白均有改善,两组CD3、NK细胞活性治疗前后差异均有显著性意义(P<0.05),且CD3、NK细胞活性组间比较差异有显著性意义(P<0.05),试验组优于对照组。[结论]心肌炎常规方案加用黄芪穴位注射,可以明显减少迁延性心肌炎患儿病情波动次数,且具有一定的免疫调节作用。 |
关键词: 迁延性心肌炎 穴位注射 病情波动次数 T细胞亚群 NK细胞 免疫球蛋白 |
DOI:10.11656/j.issn.1672-1519.2005.02.10 |
分类号: |
基金项目:天津市高等学校科技发展基金项目(991221) |
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Clinical Study on Effect of Radix Astragali Points Injection on Alleviating Fluctuation of Patient’s Condition in Children with Persistent Myocarditis |
WANG Hui,QIAO Wei-ping,HU Si-yuan
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Tianjin University of TCM, Tianjin 300193, China
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Abstract: |
[Objective] To observe the effect of Radix Astragali points injection on alleviating fluctuation of patient’s condition in children with persistent myocarditis and explore its regulating effect on immune function. [Methods] Children with persistent myocarditis were randomly divided into treatment group and control group in a ration of 1:1. On the background of routine treatment,Zusanli points injection with Radix Astragali was added to treatment group,while single routine treatment was applied to control group. The treatment course were three months and the following-up period was at least one year. Improvement of immune function and the fluctuation of patient’s condition during the following-up period were observed. [Results] The occurrence of the fluctuation of patient’s condition in both groups was reduced markedly when compared to that before treatment with significant difference between the value before and after treatment P<0.01. There was also a significant difference among each group P<0.05.Compared to control group,the value was lower in treatment group. T cells subtype,activity of NK,immunoglobulin of both groups were improved after treatment. There was a significant difference in activity of CD3 and NK of both groups before and after treatment P<0.05,and activity of CD3 and NK cell also showed significant difference among groups P<0.05.[Conclusion]Routine treatment combined with Rdix Astragali points injection can obviously reduce the occurrence of the fluctuation of the patient’s condition and possesses certain immune regulating effect. |
Key words: persistent myocarditis points injection occurrence of patient’s condition fluctuation T cells subtype NK cell immunoglobulin |