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中西医结合治疗HIV/AIDS8例临床分析
危剑安1, 宋春鑫1, 陈宇霞1, 孙存普2, 薛柳华1, 孙利民1, 白文山1, 黄霞珍1, 周伟1, 金燕1, 先宏2
1.中国中医研究院广安门医院艾滋病临床治疗中心, 北京, 100053;2.军事医学科学院, 放射医学研究所, 北京, 100850
摘要:
[目的]通过对8例人类免疫缺陷病毒/艾滋病(HIV/AIDS)患者进行中西医结合干预治疗,观察其临床疗效。[方法]8例HIV/AIDS患者在服用西药抗病毒药物双汰芝(AZT+3TC)、奈韦拉平(NVP)的同时给予中药扶正排毒胶囊,疗程6个月,治疗前后记录症状体征积分,并检测T细胞亚群、病毒载量以及丙氨酸转氨酶(ALT)、谷草转氨酶(AST)、肌酐(CR)、血液尿素氮(BUN)和体质量。[结果]治疗后症状体征积分较疗前明显下降(P<0.05),CD4计数有一定的升高(P>0.05),病毒载量在治疗6个月后全部低于检测下限;ALT恢复至正常范围;体质量保持稳定(P>0.05)。[结论]通过中西医结合干预治疗,可显著改善艾滋病患者的症状,提高免疫功能,抑制HIV的复制,降低西药的毒副作用。
关键词:  艾滋病  中西医结合治疗  临床研究
DOI:10.11656/j.issn.1672-1519.2006.02.15
分类号:
基金项目:
Clinical Analysis of 8 patients with HIV/AIDS Treated with Integrated Traditional Chinese Medicine and Western Medicine
WEI Jian-an,SONG Chun-xin,CHEN Yu-xia
Clinical Treatment center for AIDS of Guang’an-men Hospital of Chinese Academy of TCM, Beijing 100053, China
Abstract:
[Objective] To observe the therapeutic effect in 8 patients with HIV/AIDS with integrated modern medicine and TCM.[Methods] 8 cases with IV/AIDS were treated with Strengthening Zheng and eliminating toxin capsule and Combivir and NVP simultaneously for 6 months. The symptoms integral, the number of T cell subgroup, virus loading, ALT, AST, CR, BUN and body weight were recorded before and after treatment.[Results] After treatment the symptom integral was reduced (P<0.05). The CD4 count was raised in a certain degree P>0.05). All the virus loadings were located under the lower limit of test 6 months later. ALT came back to normal scope. Body weight remained in a stable condition(P>0.05).[Conclusion] The treatment of integrated modern medicine and TCM can obviously improve the symptoms and raise immune function, inhabit HIV duplication, reduce side effect of modern medicine.
Key words:  HIV/AIDS  Treatment of integrated modern medicine and TCM  Clinical research?
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