通心络胶囊不同剂量治疗冠心病心绞痛疗效观察

Clinical Effect of Different Doses of Tongxinluo Capsule on Angina Pectoris in Coronary Heart Disease

关键词:  通心络胶囊  冠心病  心气虚乏、血瘀络阻证  中医疗效

Key words:  Tongxinluo capsule  coronary heart disease  deficiency of heart-qi  syndrome with blood stasis and collateral stagnation  TCM clinical effect  electrocardiogram

摘要:

[目的]评价不同剂量通心络胶囊对冠心病心绞痛的疗效。[方法]采用随机双盲对照法,对47例冠心病心绞痛患者分为治疗组24例和对照组23例,分别采用通心络胶囊不同剂量治疗,4周后比较两组临床症状的变化。[结果]中医证候疗效:治疗组和对照组临床痊愈分别为25.0%和26.1%;显效率分别是29.2%和26.1%,无显著性差异;心绞痛疗效:治疗组和对照组显效率分别是58.3%和56.5%,无显著性差异;心电图疗效:治疗组和对照组显效率分别是16.7%和17.4%,不具有显著性差异。[结论]通心络胶囊治疗冠心病心绞痛疗效好,改善中医症状方面有优势。

Abstract:

[Objective] To evaluate the clinical effect of different doses of Tongxinluo (dredging cardiac collateral) capsule on angina pectoris in coronary heart disease. [Methods] Forty-seven patients with angina pectoris in coronary heart disease were selected and randomly divided into treatment(24 cases, treating with different doses of Tongxinluo capsule) and control group(23 cases). Double-blind and controlled method were adopted to compare the clinical symptom changes four weeks later. [Results] The improvement of TCM syndrome was better in treatment group than that of control group. The recovery and excellence rate of treatment group were individually 25.0% and 29.2%. There were no difference between two groups. Recovery and excellence rate of control group were individually 26.1% and 26.1%. Treating effect on angina pectoris hadn’t difference between the treatment group control group. The excellence rates were individually 58.3% and 58.6%. The excellence effect on electrocardiogram in treatment group hadn’t any difference with that of control group. They were individually 16.7% and 17.4%. [Conclusions] Tongxinluo capsule has a better curative effect on angina pectoris in coronary heart disease and may improve TCM syndrome.