天麻素注射液治疗椎基底动脉供血不足58例临床观察

Clinical Observation on Insufficiency of Blood Supply of Vertebral Basilar Artery Treated with Gastrodine lnjection in 58 Patients

关键词:  椎基底动脉  供血不足  天麻素注射液  经颅多普勒(TCD)

Key words:  vertebral basilar artery  insufficiency of blood supply  Gastrodine injection  TCD

摘要:

[目的]观察天麻素注射液对椎基底动脉供血不足患者的临床疗效。[方法]椎基底动脉供血不足患者116例,随机分为治疗组(天麻素注射液组)58例和对照组58例,用药14d。分别观察两组临床疗效,并检测椎基底动脉血流速度。[结果]治疗后治疗组总有效率为89.65%,优于对照组的77.59%,两组比较有统计学意义(P<0.05)。椎基底动脉血流速度的改善治疗组亦明显优于对照组。[结论]天麻素注射液可显著改善椎基底动脉血流速度,改善临床症状,对椎基底动脉供血不足有明显疗效。

Abstract:

[Objective] To study the clinical effects of Gastrodine injection in treating patients with vertebral basilar artery insufficiency(VBI).[Methods] One hundred and sixteen patients with VBI were randomly divided into treatment group treated by Gastrodin injection and control group.The clinical effects and the blood flow velocity of the vertebral basilar artery were determined with TCD in both groups.[Results] The recovery rate and the total effective rate of treatment group were 68.96% and 89.65% respectively and superior than those in control group(43.10% and 74.13%)with significant difference(P<0.05).The improvement of the blood flow velocity in the treatment group was also significantly higher than that in control group(P<0.05).[Conclusions] Gastrodine injection may increase the blood flow velocity of the vertebral basilar artery and improve the clinical symptoms.It possesses significant effect in treating the sufficiency of blood supply of the vertebral basilar artery.