血管性痴呆瘀血阻络证中医辨证体征临床研究

Clinical study on physical signs of tcm differentiation of symptoms and signs in vascular dementia with obstruction of collaterals by blood stasis

关键词:  辨证体征  诊断模型  定性诊断  瘀血阻络  Logistic回归

Key words:  differentiation of symptoms and signs  diagnostic model  qualitative diagnosis  obstruction of collaterals by blood stasis  logistic stepwise regression

摘要:

[目的]探讨血管性痴呆瘀血阻络证之定性诊断体征,为中医的体征辨证提供数理统计依据。[方法]编制血管性痴呆中医体征调查表,采用非条件性Logistic逐步回归筛选瘀血阻络证之辨证体征,建立血管性痴呆瘀血阻络证之辨证体征诊断模型,并给出各体征对瘀血阻络证定性诊断的影响度。[结果]发现耳轮色晦暗、眼周色黑、唇色紫黯等3项体征对血管性痴呆瘀血阻络证之定性诊断有重要意义。[结论]这项研究不仅有利于血瘀证诊断标准的客观化研究,而且有利于中医其他证候诊断标准的客观化研究。

Abstract:

[Objective] To explore the physical signs for qualitative diagnosis in vascular dementia with obstruction of collaterals by blood stasis and provide a mathematic statistical evidence for TCM differentiation of physical signs. [Methods] A investigation table of physical signs in TCM for vascular dementia was established. Using unconditional logistic stepwise regression screening for the physical signs of obstruction of collaterals by blood stasis a model of differentiation diagnosis for physical signs of syndrome of obstruction of collaterals by blood stasis in vascular dementia was reproduced and the influence of each physical signs on the qualitative diagnosis obstruction of collaterals by blood stasis was observed. [Results] It was found that dark of helix and periocular tissue and darken lip had important effect on the qualitative diagnosis of obstruction of collaterals by blood stasis in vascular dementia. [Conclusions] The study is beneficial not only for the objective investigation of diagnostic standards of the syndrome of blood stasis and also for that of other syndrome in TCM.