中药消癖汤治疗高泌乳素血症临床观察

Treatment of hyperprolactinemia with Xiaopi Decotion

关键词:  高泌乳素血症  中医药疗法  消癖汤  溴隐停

Key words:  hyperprolactinemia  traditional Chinese medicine treatment  Xiaopi Decotion  ergolactin

摘要:

[目的]观察中医药治疗高泌乳素血症(HPRL)的临床疗效。[方法]将453例HPRL患者随机分成两组,治疗组(366例)用疏肝清热化痰之中药组方治疗,对照组(87例)用溴隐停治疗,观察血中催乳素(PRL)和相关激素水平及临床症状体征变化情况,并进行随访。[结果]治疗组与对照组总有效率分别为94.8%,94.2%,两组血清PRL均较治疗前显著降低,促卵泡成熟激素(FSH)、雌二醇(E₂)均较治疗前显著提高。[结论]中医药治疗高泌乳素血症与溴隐停作用相同,但无不良反应,且复发率低。

Abstract:

[Objective] To observe the curative effect of traditional Chinese medicine in treating hyperprolactinemia.[Methods] Four hundreds and fifty-three patients with hyperprolactinemia(HPRL) were randomly divided into TCM treatment group(366 cases treated with Shugan(dispersing the stagnated liver-QI) Qingre(clearing away heat) Huatan(resolving phlegm) and ergolactin control group(87 cases). The change of blood prolactin(PRL),correlated hormone level and clinical symptoms and physical signs were observed and followed up.[Results] The total effect rate of treatment and control group was 94.8% and 94.2% respectively. The PRL level of two groups after treatment was obviously lower than that of before treatment. The FSH and E₂ level of two groups after treatment was obviously higher than that of before treatment.[Conclusions] The curative effect of traditional Chinese medicine group has a same curative effect compared with that of ergolactin group in treating hyperprolactinemia. But traditional Chinese medicine has not adverse reaction and has lower recurrence rate than that of ergolactin group.