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| 摘要: |
| [目的] 探讨痤疮颗粒对痤疮患者血清中细胞因子变化。[方法] 采用放射性免疫学方法检测痤疮颗粒对痤疮患者血清中白细胞介素-8(IL-8),肿瘤坏死因子-α(TNF-α)水平的影响。[结果] 应用痤疮颗粒治疗痤疮患者后,其血清中的IL-8和TNF-α水平均较用药前有显著变化(P<0.01);并且疗后患者血清中IL-8和TNF-α水平与正常对照组无差异(P>0.05)。[结论] 痤疮颗粒能够改变痤疮患者血清中细胞因子水平。 |
| 关键词: 痤疮 细胞因子 痤疮颗粒 |
| DOI:10.11656/j.issn.1672-1519.2007.06.05 |
| 分类号: |
| 基金项目:黑龙江省科技厅资助项目(GC04C42702)。 |
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| Effect of acne granule on IL-8 and TNF-α level in serum in patients with acne |
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WANG Ya-xian, WANG Ting-ting, GUAN Hong-jie
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| Abstract: |
| [Objective] To investigate the effect of Acne Granule on serum IL-6 and TNF-α level in acne patients.[Methods] By radioimmunity technique the effect Acne Granule on serum cytokine of acne patients was observed.[Results] Treated with Acne Granule, serum IL-8 and TNF-α of patients were remarkably different from that before treatment (P<0.01) and without difference when compare with normal group(P>0.05). Meanwhile, after treatment with Acne Granula serum IL-8 and TNF-α of patients were also different remarkably when compared with the level before treatment (P<0.01) and almost the same with normal group(P>0.05).[Conclusions] Acne Granule can change the level of the serum cytokine in acne patients. |
| Key words: acne cytokine acne granula |