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痤疮颗粒对痤疮患者血清中白细胞介素-8和肿瘤坏死因子-α水平的影响
王亚贤, 王婷婷, 关红捷, 沈小平, 王慧, 张友堂
作者单位
王亚贤  
王婷婷  
关红捷  
沈小平  
王慧  
张友堂  
摘要:
[目的] 探讨痤疮颗粒对痤疮患者血清中细胞因子变化。[方法] 采用放射性免疫学方法检测痤疮颗粒对痤疮患者血清中白细胞介素-8(IL-8),肿瘤坏死因子-α(TNF-α)水平的影响。[结果] 应用痤疮颗粒治疗痤疮患者后,其血清中的IL-8和TNF-α水平均较用药前有显著变化(P<0.01);并且疗后患者血清中IL-8和TNF-α水平与正常对照组无差异(P>0.05)。[结论] 痤疮颗粒能够改变痤疮患者血清中细胞因子水平。
关键词:  痤疮  细胞因子  痤疮颗粒
DOI:10.11656/j.issn.1672-1519.2007.06.05
分类号:
基金项目:黑龙江省科技厅资助项目(GC04C42702)。
Effect of acne granule on IL-8 and TNF-α level in serum in patients with acne
WANG Ya-xian, WANG Ting-ting, GUAN Hong-jie
Abstract:
[Objective] To investigate the effect of Acne Granule on serum IL-6 and TNF-α level in acne patients.[Methods] By radioimmunity technique the effect Acne Granule on serum cytokine of acne patients was observed.[Results] Treated with Acne Granule, serum IL-8 and TNF-α of patients were remarkably different from that before treatment (P<0.01) and without difference when compare with normal group(P>0.05). Meanwhile, after treatment with Acne Granula serum IL-8 and TNF-α of patients were also different remarkably when compared with the level before treatment (P<0.01) and almost the same with normal group(P>0.05).[Conclusions] Acne Granule can change the level of the serum cytokine in acne patients.
Key words:  acne  cytokine  acne granula
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