| 摘要: |
| [目的]建立清燥润肺合剂的质量标准。[方法]采用薄层色谱法(TLC)对制剂中甘草、麦门冬、枇杷叶进行定性鉴别,采用高效液相法(HPLC)测定制剂中甘草酸的含量。[结果]TLC色谱中能检出甘草、麦门冬、枇杷叶,甘草酸在0.2031～1.6921μg范围内具有良好线性关系(r=0.9999),平均回收率为98.07%(RSD=1.76%)。[结论]该方法简便可靠,重现性好,可用于该制剂的质量控制。 |
| 关键词: 清燥润肺合剂 质量标准 HPLC TLC |
| DOI：10.11656/j.issn.1672-1519.2008.04.31 |
| 分类号: |
| 基金项目: |
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| Research on the quality standard of Qingzaorunfei mixture |
|
Zhao yan-ling1,2
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1.Jiangsu Union Technical Institue, Lianyungang TCM &2.Pharmaceutical Branch, Lianyungang 222006, China
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| Abstract: |
| [Objective] To establish the quality standard of Qingzaorunfei composition. [Methods] Radix et Rhizoma glycyrrhizae, Radix ophiopogonis and Folium eriobotryae in Qingzaorunfei composition were identified by TLC. The content of glycyrrhizic acid in Qingzaorunfei composition was determined by HPLC. [Results] Radix et Rhizoma glycyrrhizae, Radix ophiopogonis were detected by TLC. The linear correlation was good (r=0.999 9) when The content of glycyrrhizic acid was in 0.203 1～1.692 1μg. The mean recovery rate was 98.07% (RSD=1.76%). [Conclusion] The method is simple and reliable with good reproducibility, and can be used to control the quality of Qingzaorunfei composition. |
| Key words: Qingzaorunfei composition quality standard HPLC TLC |
