| 摘要: |
| [目的]探讨抑郁症患者临床汉密顿抑郁量表(HAMD)量表评分情况及7个因子分与中医证候要素间的关系。[方法]病证结合的指道思想下,采用临床流行病学横断面调查的方法,在全国6个中心开展为期3个月的临床调查,由通过培训的专业医生对患者进行24项HAMD量表评定,并开放式采集临床调查医生对患者的经验辨证,提取证候要素,并应用Epidata3.0软件建立数据库,运用SPSS13.0软件进行描述性统计分析及相关分析。[结论]共调查抑郁症患者604人,HAMD总分值的平均分为27.1457分;最低分8分(4例,0.7%);最高分53分(3例,0.5%);出现频次最多的总分值为23分(41例,6.8%);其中焦虑因子与证候要素脾、热关系密切;体质量因子与证候要素脾、气虚关系密切;认知因子与证候要素肝、脑关系密切;日夜变化因子与证候要素胆、胃、痰关系密切;阻滞因子与证候要素心、肺、痰、神关系密切;睡眠因子与证候要素胃关系密切;绝望因子与证候要素血瘀、痰、热关系密切。[结论]7个因子相关的病位类证候要素主要有:脾、胃、肝;病性类证候要素有:痰、热。 |
| 关键词: 抑郁症 HAMD量表 证候要素 |
| DOI：10.11656/j.issn.1672-1519.2009.06.30 |
| 分类号: |
| 基金项目:“973”国家重点基础研究发展计划-“证候规范及其与疾病、方剂相关的基础研究”课题1(2003CB517101)资助 |
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| Correlation analysis between factor scores and syndrome essence of hamilton depression scale (HAMD) in patients with depression |
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ZHAO Yan1, LI Xue2, XU Wen-jie3
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1.The Basic Medicine College of Beijing University of TCM, Beijing 100029, China;2.Beijing Huilongguan Hospital, Beijing 102208, China;3.Beijing TCM Institute, Beijing 100010, China
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| Abstract: |
| [Objective] To investigate the relationship between the scores of the Hamilton Depression Scale (HAMD) and seven factors and syndrome essence of traditional Chinese medicine. [Methods] HAME 24 items on patients in six centers at the same time (three months) were evaluated by the ways of epidemiological transect investigation, combining the disease and syndrome and the qualified clinician rate scale. The clinical experiences and syndrome-essences were collected.[Results] A total of 604 patients with depression were investigated: the total averaging HAMD score was 27.1457, the lowest was 8 point, the highest was 53 point; the syndrome-elements of location: liver was closely associated with the authentication factor, spleen was closely associated with the anxiety factor and weight factor; stomach was closely associated with the diurnal variation factors and sleep factor. The syndrome-elements of nature: Qi deficiency was closely associated with the weight factor; blood stasis was closely associated with the desperation factor; sputum and diurnal variation factor, retardation factor, desperation factor were closely associated. [Conclusion] Correlation analysis between syndrome essences and HAMD factors suggested that a close relationship between syndrome-essences and certain features in the psychopathology was existed. The main positions of disease syndrome factors were spleen, stomach and liver. The main pathology factors were phlegm and heat. |
| Key words: depression hamilton depression scale syndrome essence |
