强心通脉颗粒治疗慢性心力衰竭30例的临床研究

Clinical observation on Qiangxin Tongmai granule in treating chronic cardiac failure in 30 patients

关键词:  参草通脉颗粒  慢性心衰  6min步行法  中医证候

Key words:  granule of Qiangxin Tongmai  chronic heart failure  6 minutes walking distance  Traditional Chinese Medicine syndrome

摘要:

[目的]观察强心通脉颗粒治疗慢性心衰的临床疗效及安全性。[方法]观察60例慢性心衰患者,并随机分为治疗与对照组,每组30例。对照组采用西医常规治疗;治疗组采用西医常规治疗加强心通脉颗粒,用药疗程均为4周。观察患者的疗效、6 min步行距离、心功能变化及中医症候积分变化情况,并分析药物安全性。[结果]治疗组与对照组总有效率分别为86.7%、63.3%,两组有显著性差异(P<0.01);两组治疗后,比较6 min步行距离、心功能及证候积分等变化情况,治疗组优于对照组(P<0.01),具有显著统计学差异;心功能指标(P<0.05)有统计学差异,证明本药安全有效。[结论]强心通脉颗粒对于慢性心衰患者疗效确切,能够改善患者心功能,降低中医证候积分,提高慢性心衰患者生活质量。

Abstract:

[Objective] To observe the therapeutic effect and safety of granule of Qiangxin Tongmai in treating patients with chronic heart failure.[Methods] Sixty patients with chronic heart failure were randomly divided into two groups:the treatment group and the control group.The patients of control group were treated with routine Western medicine,while those of treatment group were treated with the granule of Qiangxin Tongmai for 4 weeks.Then the therapeutic effects were examined by testing the distance of 6 minutes walking,the function of heart,and the integrated score of TCM syndrome and the safety of the drug.[Results] The total effect ratio of treatment group was 86.7% and that of control group was 63.3%(P<0.01).Compared with the control group,the 6 minutes walking distance,the function of heart,and the TCM syndrome integrated score were significantly superior in treatment group(P<0.01).[Conclusion] The granule of Qiangxin Tongmai has a definitely therapeutic effect in treating chronic heart failure,may improve patients’ heart function,decrease the integrated score of TCM syndrome and can improve the patients’ quality of life as well.