血必净注射液灌肠治疗外科脓毒症的疗效观察

Observation of curative effect of Xuebijing injection enema on surgical sepsis

关键词:  脓毒症  血必净注射液  D-二聚体

Key words:  sepsis  Xuebijing injection  D-dimer

摘要:

[目的] 观察血必净注射液保留灌肠对外科脓毒症的疗效.[方法] 外科脓毒症患者60例,随机分为观察组和对照组各30例,均采用常规早期液体复苏,抗感染等综合治疗.观察组加用血必净注射液保留灌肠治疗,每日1次,1周后观察血象、白细胞计数(WBC)、C反应蛋白(CRP)、D-二聚体的变化.[结果] 治疗1周后,观察组总有效率为86.7%、对照组总有效率为60%;WBC计数、CRP、D-二聚体,观察组与对照组比较,差异均有统计学意义(P < 0.05).中性粒细胞数比较两组无明显差异.[结论] 血必净注射液保留灌肠可促进脓毒症的好转,改善凝血紊乱状态.

Abstract:

[Objective] To observe the effects of retention enema by Xuebijing injection in treating surgical patients with sepsis. [Methods] The 60 cases of surgical patients with sepsis were randomly divided into observation group and control group with 30 cases in each group. The early fluid resuscitation and anti-infective therapy were used in both groups, while the observation group was added with retention enema of Xuebijing injection, once a day. The therapeutic effects, including hemogram white blood cell count (WBC), C-reactive protein(CRP), D-dimer changes were then observed one week later. [Results] After treatment for 1 week, the total effective rate was 86.7% in treatment group and 60% in control group. The WBC, CRP, and D-dimer were all significantly different between the observation group and the control group (P < 0.05). But the neutrophil counts had no significant difference between the two groups. [Conclusion] Xuebijing retention enema can promote the improvement of sepsis and coagulation disorder.