基于临床报道的407例肝炎肝硬化典型病例的治疗方药分析

Analysis of traditional Chinese prescriptions and medicine based on clinical reports in 407 typical cases with typical hepatitis cirrhosis

关键词:  肝炎肝硬化  处方  中药

Key words:  hepatitis cirrhosis  prescription  traditional Chinese medicine

摘要:

[目的] 分析治疗肝炎肝硬化的常用方、药。[方法] 以“肝硬化”、“中医”、“证”等为主题词,系统检索中国学术期刊网络出版总库、中文科技期刊全文数据库与中国生物医学文献数据库近20年来所有相关文献,选取其中具有肝炎肝硬化典型病例有效治疗的文献,将所用治疗方、药运用SPSS18.0建立数据库,并进行频次分析。[结果] 符合纳入分析标准的文献326篇,患者407例,属于代偿期和失代偿期的例数分别为80和327例,其中失代偿期的病例均有腹水的并发症;407例的治疗中,只有98例选用成方加减,其余均采用自拟方;选用的药物涉及299味、19类,两期用药有共性也有不同侧重。[结论] 肝炎肝硬化治疗中使用成方较少、自拟方较多;使用中药的种类和味数较多,两期用药既有共同之处,也有各自侧重,反映了该病的复杂病机特点及辨病和辨证论治的特点。

Abstract:

[Objective] To analyze the commonly used traditional Chinese prescriptions and medicine in treating hepatitis cirrhosis. [Methods] Using "cirrhosis", "traditional Chinese medicine" and "syndrome" as the key words, systemically searching all the correlated articles in Chinese literature databases for a course of 20 years, a database of hepatitis cirrhosis's, traditional Chinese prescriptions and medicine was established by SPSS18.0 and the using frequency was analyzed. [Results] There were 407 patients with hepatitis cirrhosis in the clinical reports. Among them 80 were compensated cirrhosis and 327 decompensated cirrhosis, whose complication was ascites. In these 407 treated cases, only 98 cases treated with the modified patent prescriptions and the others with the self-prescribed ones. The selected herbs involved 299 ingredients and 19 kinds. The herbs used in both phases had similar characteristics but different major point. [Conclusion] In the treatment of hepatitis cirrhosis the patent prescriptions are less used but the self-prescribed ones are widely used. Many kinds and recipes of traditional Chinese medicine are used. Because of the complex pathogenesis and syndrome differentiation and treatment, the prescriptions and traditional Chinese medicine used in two stages are different.