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肾康注射液治疗早期糖尿病肾病的临床观察
马继伟1,2, 王宏天2, 刘培娜2, 张翥2
1.天津中医药大学, 天津 300193;2.河南中医学院第一附属医院, 郑州 450000
摘要:
[目的] 观察肾康注射液治疗早期糖尿病肾病的疗效。[方法] 将患者随机分为治疗组36例,对照组40例,两组均予以优质低蛋白饮食、控制血压、血糖,另外治疗组予以肾康注射液每日100 mL,疗程4周。观察两组患者治疗前后空腹血糖(FBG)、餐后2 h血糖(PBG)、甘油三酯(TG)、胆固醇(TC)、血纤维蛋白原(Fg)、α-微球蛋白(α-MG)、24 h尿蛋白定量(24 h UP)、尿N-乙酰β葡萄糖苷酶(NAG)、尿白蛋白排泄率(UAER)的变化。[结果] 治疗组治疗后与同组治疗前及对照组治疗后比较,FBG、PBG、TG、TC、Fg、α-MG、NAG、UAER、24 hUP明显改善(P<0.05),对照组治疗前后比较差异无统计学意义(P>0.05)。[结论] 肾康注射液能够提高临床疗效延缓糖尿病肾病进展。
关键词:  肾康注射液  糖尿病肾病  临床观察
DOI:10.11656/j.issn.1672-1519.2013.09.05
分类号:
基金项目:国家自然科学基金资助项目(81273950)
Clinical observation on Shenkang injection in treating diabetic renopathy in early period
MA Ji-wei1,2, WANG Hong-tian2, LIU Pei-na2, ZHANG Zhu2
1.Tianjin University of TCM, Tianjin 300193, China;2.The First Affiliated Hospital of Henan University of TCM, Zhengzhou 450000, China
Abstract:
[Objective] To investigate the therapeutic effect of Shenkang injection on diabetic kidney disease in early period. [Methods] The patients were randomly divided into treatment group (36 cases) and control group (40 cases). Both groups were given quality diet with low protein. Blood pressure and plasma glucose were controlled. In addition, the patients in treatment group were given with shenkang injection, 100 mL/d for four weeks. Fasting blood glucose(FBG), 2-hour postprandial glucose (PBG), triglyceride (TG), total cholesterol (TC), blood fibrinogen (Fg), α-microglobulin (α-MG), twenty-four-hour urine protein quantitation (24 h UP), NAG and UAER were examined. [Results] Compared with those in control group, the amount of FBG, PBG, TG, TC, Fg, α-MG, NAG, UAER and 24-hour urine protein were markedly decreased in treatment group(P<0.05). [Conclusion] Shenkang injection can delay the development of diabetic renopathy.
Key words:  Shenkang injection  diabetic kidney disease  clinical observation
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