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| 五田保肝颗粒的提取工艺研究 |
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黄美菊1, 刘佩莉2, 孔令钰2, 陈灵芝1, 李楠2, 毕业东3, 王倩2
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1.天津中医药大学, 天津 300193;2.天津市医药科学研究所药代动力学室, 天津 300020;3.天津市汉沽区中医医院, 天津 300480
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| 摘要: |
| [目的] 优化五田保肝颗粒的提取工艺。[方法] 采用正交实验设计,以干膏得率、总黄酮含量和五味子醇甲含量为评定指标,通过多指标综合评分优选五田保肝颗粒的提取工艺。[结果] 最佳提取工艺条件为12倍量40%乙醇提取3次,每次2 h。[结论] 所确定的最佳提取工艺合理,有效成分提取效率高。 |
| 关键词: 五田保肝颗粒 正交实验 综合评分法 |
| DOI：10.11656/j.issn.1672-1519.2013.09.18 |
| 分类号: |
| 基金项目:天津市中医药管理局中医中西医结合科研课题资助项目(11084) |
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| Study on the extracting procedure of Wutian Baogan granules |
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HUANG Mei-ju1, LIU Pei-li2, KONG Ling-yu2, CHEN Ling-zhi1, LI Nan2, BI Ye-dong3, WANG Qian2
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1.Tianjin University of TCM, Tianjin 300193, China;2.Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China;3.Hangu Hospital of Traditional Chinese Medicine, Tianjin 300480, China
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| Abstract: |
| [Objective] To optimize the extraction process for Wutian Baogan granules.[Methods] The orthogonal test was employed and taking the extraction rate and the content of flavonoids and schisandrinas the index,using comprehensive evaluation score the extraction process of Wutian Baogan granules was optimized.[Results] The optimal extraction technique conditions were as follows: 12 times of amount of 40% ethanol, extracted for 3 times, each time for 2 hours.[Conclusion] The optimized extraction technology is rational and the extraction rate of the active ingredients is high. |
| Key words: Wutian Baogan granule orthogonal test comprehensive evaluation method |
