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化浊和血颗粒治疗缺血性脑血管病临床疗效总结
宗寿健1, 胡晓洁2, 王兴臣1
1.山东中医药大学第二附属医院神经内科, 济南 250001;2.山东中医药大学2011 级硕士研究生, 济南 250355
摘要:
[目的] 观察化浊和血颗粒对缺血性脑血管病的临床疗效。[方法] 200例缺血性脑血管病患者,随机分为观察组100例、对照组100例,观察组在西医综合治疗的基础上加用化浊和血颗粒,对照组予以西医综合治疗,疗程为3个月。[结果] 化浊和血颗粒能够降脂、降低血浆黏度、及纤维蛋白原浓度,降低超敏,反应蛋白及血同型半胱氨酸水平,并且能够显著改善缺患者神经功能缺损评分。[结论] 在西医综合治疗基础上,化浊和血颗粒具有多靶点、多角度的协同治疗效果,能够起到降脂抗凝、防止动脉粥样硬化斑块形成、改善血液流变学、抗炎及改善患者神经功能缺损评分,达到全面防治缺血性脑血管疾病及提高预后的目的。
关键词:  缺血性脑血管病  血浊  化浊和血颗粒  临床疗效
DOI:10.11656/j.issn.1672-1519.2014.04.03
分类号:
基金项目:山东省自然科学基金资助项目(2009ZRB14056);山东省中医药科学发展计划项目(2009-119);山东省中医药科技发展计划重点项目(2013Z003-4)。
Clinical summary of Huazhuo Hexue granules in treating ischemic cerebrovascular disease
ZONG Shou-jian1, HU Xiao-jie2, WANG Xing-chen1
1.Department of Neurology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, China;2.The Class of 2011 Master's Graduate Student, Shandong University of Traditional Chinese Medicine, Jinan 250001, China
Abstract:
[Objective] To observe the clinical efficacy ofHuazhuo Hexue (regulating lipid and adjusting flowof blood) granules in ischemic cerebrovascular disease. [Methods] The 200 patients with ischemic cerebrovascular disease were randomly divided into observation group and control group, 100 patients in each group. The observation group treated by Western medicine comprehensive therapy based on the use of lipid-lowering and Huazhuo Hexue granules, and the control group received comprehensive treatment of Western medicine. The treatment course was 3 months. [Results] Huazhuo Hexue granules could reduce plasma viscosity, fibrinogen concentration, high-sensitivity of C-reactive protein and serum homocysteine levels, and significantly improve the deficiency of neurological function in patients. [Conclusion] Huazhuo Hexue granule have a synergistic therapeutic effect with multi-target and multi-angle. It could play a lipid-lowering and anticoagulant effect and prevent the formation of atherosclerotic plaque and improve the blood rheology. having an anti-inflammatory and improving neurological function in patients, achieving a comprehensive prevention and treatment in patiens with ischemic cerebrovascular disease. Huazhuo Hexue granule could achieve the purpose of improving the prognosis.
Key words:  ischemic cerebrovascular disease  turbid blood  Huazhuo Hexue granule  clinical efficacy
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