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养阴清肺汤加减治疗肺癌125I粒子植入术后早期放射性肺损伤的疗效观察
毕海1,2, 方文岩3, 陈薇2
1.天津中医药大学研究生院, 天津300193;2.天津中医药大学第一附属医院影像科, 天津300193;3.天津中医药大学第一附属医院肿瘤科, 天津300193
摘要:
[目的] 观察养阴清肺汤加减治疗肺癌125I粒子植入术后早期放射性肺损伤的疗效。[方法] 选取肺癌125I粒子植入术后急性放射性肺损伤患者80例,随机分为对照组和治疗组各40例,治疗组用养阴清肺汤另加入降气化痰、清热的中药治疗,对照组按药敏培养结果或经验性敏感抗生素治疗,再配伍短程、高效激素冲击治疗,4周后按统一疗效标准进行评定。[结果] 治疗组的有效率明显高于对照组(P<0.05)。[结论] 养阴清肺汤加减在治疗肺癌125I粒子植入术后肺损伤中疗效显著。
关键词:  养阴清肺汤加减|肺癌|125I粒子植入术|放射性肺损伤
DOI:10.11656/j.issn.1672-1519.2014.06.05
分类号:
基金项目:
Observation of modified Yangyin Qingfei decoction in treating radiation induced lung injury after 125I seeds implantation
BI Hai,FANG Wen-yan,CHEN Wei
1.Department of Radiology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.The Department of Tumor, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:
[Objective] To investigate the effects of Yangyin Qingfei decoction in treating the patients diagnosed with acute radiation induced lung injury after radioactive seeds of 125I implantation for lung tumor. [Methods] Eighty patients with acute radiation induced lung injury after radioactive seeds implantation were recruited and randomly divided into the treatment group and the control group, 40 cases in each group. Traditional Chinese medicine of Yangyin Qingfei decoction was used for the treated group, while antibiotics with short-term hormone therapy were used in the control group. The results were evaluated using the same standard 4 week later. [Results] The effective rate in the treated group was significantly higher than that in the control group (p<0.05). [Conclusion] Yangyin Qingfei decoction has significant effect in the treatment of acute radiation induced lung injury after radioactive seeds implantation.
Key words:  Yangyin Qingfei decoction|lung cancer|125I seeds implantation|radioactivity lung injury
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