| 摘要: |
| [目的] 分析丹参注射液临床不良反应的特征和可能原因，为临床用药提供参考。[方法] 检索2002-2012年中国知网（CNKI）数据库收录的国内关于丹参注射液导致不良反应的167例病例，对各种不良反应进行统计分析，尝试分析相关并发症的原因，并寻找预防措施。[结果] 167例丹参注射液临床不良反应中，以过敏反应为主，初步推测与丹参注射液有效成分无关，而发生率为2.99%的出血性不良反应可能为丹参注射液有效成分所致。[结论] 大多丹参注射液的不良反应可能与其主要有效成分无关。其有效成分可能会导致出血在使用过程中应引起注意。 |
| 关键词: 丹参注射液 有效成分 不良反应 |
| DOI：10.11656/j.issn.1672-1519.2014.07.12 |
| 分类号: |
| 基金项目:国家自然科学基金面上项目（81273936） |
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| Analysis on clinical adverse reactions of Salvia injection in 167 patients |
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GUO Wei, LI Na, HUANG Yu-hong
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The Second Affiliated Hospital of Tianjin University of Traditional Chinese Mdeicine, Tianjin 300150, China
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| Abstract: |
| [Objective] To analyze the characteristics and possible reasons of the clinical adverse reactions of Salvia injection for providing some clinical reference. [Methods] The 167 cases of adverse reactions of Salvia injection were searched from 2002 to 2012 on CNKI database. All kinds of adverse reactions were counted and the reasons of related complications were analyzed for finding the preventive measures. [Results] Anaphylactic reaction was the main adverse reactions of clinical adverse reactions of Salvia injection in 167 patients and we speculated that it was not related with the active ingredients in Salvia injection. The bleeding adverse reactions, however, may be related with active ingredients and its occurrence rate was 2.99%. [Conclusion] Most of the adverse reactions of Salvia injection may be independent of its main active ingredient. The active ingredient may lead into bleeding and it should be paid on during its use. |
| Key words: Salvia injection active ingredient adverse reaction |
