多囊卵巢综合征合并代谢综合征的中医证型特征研究

Research of characteristics of Chinese medicine types and polycystic ovary syndrome with metabolic syndrome

关键词:  多囊卵巢综合征  代谢综合征  中医证型  特征

Key words:  polycystic ovary syndrome  metabolic syndrome  traditional Chinese medicine syndrome  feature

摘要:

[目的] 探讨多囊卵巢综合征(PCOS)合并代谢综合征(MS)临床指标的中医证候特征。[方法] 将91例PCOS合并MS患者利用中医四诊分类,观察一般情况及临床理化指标,包括年龄、身高、体质量、腰围、臀围、血压(BP),测定甘油三酯(TG)、高密度脂蛋白(HDL)、空腹血糖(FPG).[结果] 就诊的91例患者中脾虚痰湿证42.86%,痰瘀互结证29.67%,肾虚血瘀证16.48%,肾虚肝郁证10.99%.BP、HDL、FPG水平各证组间比较,差异无统计学意义(P>0.05);肾虚血瘀证TG水平与脾虚痰湿证比较,差异有统计学意义(P<0.05);脾虚痰湿证与其他证型比较,腰围、臀围、腰臀比显着升高。[结论] PCOS合并MS患者不同证型间具有其内在的特征,尚需大样本进行深入研究。

Abstract:

[Objective] To analysis clinical features with traditional Chinese medicine(TCM) syndrome indicators of polycystic ovary syndrome (PCOS) with metabolic syndrome(MS). [Methods] The 91 cases of MS patients with PCOS combined use of four diagnostic categories, and clinical observation general physical and chemical indicators, including age, height, weight, waist circumference, hip circumference, blood pressure (BP), measured triglyceride (TG), high density lipoprotein (HDL), fasting plasma glucose (FPG). [Results] In the 91 patients, the spleen phlegm 42.86%, 29.67% of phlegm and blood stasis, kidney and blood stasis syndrome 16.48%, 10.99% kidney liver permits. BP, HDL, FPG level between the syndrome group, the difference was not significant. Kidney and blood stasis syndrome TG levels compared with spleen phlegm, the difference was statistically significant(P<0.05). Spleen phlegm comparison with other syndromes, waist circumference, hip circumference, waist-hip ratio was significantly increased. [Conclusion] PCOS merger between MS patients with different syndromes and general physical and chemical indicators has its inherent characteristics.