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中药“神曲”发酵工艺及质量标准研究进展
刘双1,2, 杨静1,2, 江振作1,2, 王跃飞1,2
1.天津中医药大学, 天津市现代中药重点实验室——省部共建国家重点实验室培育基地, 天津300193;2.天津国际生物医药联合研究院, 中药新药研发中心, 天津300457
摘要:
神曲是由面粉和/或麦麸、苦杏仁、赤小豆、青蒿、苍耳、辣蓼按照一定比例混匀后发酵而成的复方中药。性温,味甘、辛;归脾、胃、大肠经,具有健脾消食,理气化湿的功效。作为传统曲剂,神曲的发酵工艺直接影响产品的质量。本文就神曲的发酵工艺和质量标准进行系统的综述。
关键词:  神曲  发酵工艺  质量标准
DOI:10.11656/j.issn.1672-1519.2015.05.17
分类号:
基金项目:重大新药创制科技重大专项(2015ZX09J15102-004)、“973”计划前期研究专项(2012CB723504).
Research progress of fermentation technology and quality standard of Shenqu
LIU Shuang1,2, YANG Jing1,2, JIANG Zhen-zuo1,2, WANG Yue-fei1,2
1.Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Research and Development Center of Traditional Chinese Medicine, Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin 300457, China
Abstract:
Shenqu is a traditional compound medicine manufactured by fermentation, which is made of flour and/or bran, Armeniacae Semen Amarum, Vignae Semen, Artemisiae Annuae Herba, Xanthii Fructus and Marshpeper Smartweed Herb. It is warm in property, acrid-sweet in taste and distributed to spleen, stomach, colon. Shenqu has the function of invigorating spleen forpromoting digestion and regulating Qi-flowing for eliminating dampness. As a traditionalfermented medicine, the fermentation processdirectly affects the quality. The review systematically focuses on the fermentation technology and quality standard of Shenqu.
Key words:  Shenqu  fermentation technology  quality standard
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