摘要: |
感染性疾病不断进化并对现有药物产生抗药性,而天然产物为抵抗细菌性和真菌性疾病提供了新药研究的先导化合物。概述近年来抗细菌和抗真菌的天然产物及其生物活性的研究进展,为该类药物的深入研究和开发利用提供数据支撑和参考。 |
关键词: 天然产物 抗菌 先导化合物 感染性疾病 生物活性 |
DOI:10.11656/j.issn.1672-1519.2016.02.17 |
分类号: |
基金项目:国家自然科学基金资助项目(81403198)。 |
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Research progress on anti-bacterial and anti-fungal effects of natural products |
YANG Shu1, GAO Shan2
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1.Tianjin Fourth Central Hospital, Tianjin 300140, China;2.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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Abstract: |
With the evolution of infectious disease, many of them develop resistance to existing pharmaceuticals. Natural products provides novel leads against bacterial and fungal diseases. In this paper, we make reviews for antifungal agents and antibacterial agents leads from natural products and their bioactivity, provide available information for more research and exploitation. |
Key words: natural product anti-bacterial lead compound infectious disease bioactivity |