| 摘要: |
| 中医应用富碘中药治疗瘿病历史悠久，疗效确切，但碘摄入过多、过久易导致多种甲状腺疾病的发生。准确、有效的测定中草药的碘含量具有重要意义，既可明确各味中药的碘含量，也能指导临床医师根据碘含量选择适当的中药治疗瘿病。当前，用于测定中药碘含量的方法主要包括催化法、滴定法、电感耦合等离子质谱法（ICP-MS）等，其中ICP-MS因快速、准确、检出限低更适于中药的碘测定。临床治疗瘿病时，不可盲目否定富碘中药，应辨病与辨证相结合，并根据中药碘含量选择合适的药物和疗程。 |
| 关键词: 碘 中药 瘿病 测定方法 |
| DOI：10.11656/j.issn.1672-1519.2018.03.22 |
| 分类号:R265 |
| 基金项目:江苏省中医局省级条件建设与民生科技专项基金项目（BL2013040）；江苏省省级中医名科建设项目（2100202）。 |
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| Clinical application for determination of iodine in Chinese herbal medicine |
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XIANG Pingping1, WANG Xu2, LIU Chao1
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1.Endocrine and Metabolism Area Affiliated Hospital of Integrated Chinese and Western Medicine, Jiangsu Prouince Academy of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing 210028, China;2.The First Clinical Medicine College, Nanjing University of Chinese Medicine, Nanjing 210029, China
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| Abstract: |
| The iodine-rich Chinese herbal medicine has been applied to treat thyroid diseases effectively for thousands of years, though excessive iodine intake leads to various thyroid diseases. Accurate and effective determination of iodine is of great importance for clinicians to identify the iodine content and to choose appropriate herbal medicine in treating Yingbing. Nowadays, effective analytical methods for iodine content in herbal medicine include spectrophotometry methods, titration methods, the inductively coupled plasma mass-spectrometer methods (ICP-MS), among those, ICP-MS has been described as fast, accurate and low detection limit for the quantification of herbal medicine. Clinicians need to select appropriate herbal medicine according to the iodine content,and combine diseases differentiation with syndrome differentiation in clinical application, instead of refusing iodine-rich herbal medicine in treating graves' disease. |
| Key words: iodine herbal medicine Yingbing determination method |
