生肌膏对深Ⅱ度烧伤创面愈合后期的临床疗效观察

Observation on the clinic effect of the Shengji ointment in the later stage on deep second degree burn wound healing

关键词:  深Ⅱ度烧伤  创面  生肌膏

Key words:  deep second degree burn  wound  Shengji ointment

摘要:

[目的] 观察生肌膏在深Ⅱ度烧伤创面愈合后期的临床效果。[方法] 将就诊的60例深Ⅱ度烧伤患者采用随机数字表法随机分为对照组和观察组，每组各30例。对照组患者创面外用磺胺嘧啶银霜剂，每1~2日换药1次，直至完全愈合。观察组患者早期创面外用磺胺嘧啶银霜剂，伤后15 d开始外用生肌膏，每1~2日换药1次，直至创面完全愈合。视觉模拟评分法（VAS）评价用药后创面静息情况下疼痛情况，记录2组患者平均愈合时间，温哥华瘢痕量表（VSS）评价愈合后创面的形态，记录创面愈合后2周内水疱发生率，对所得数据进行统计学处理。同时记录研究过程中出现的不良反应。[结果] 观察组静息状态下疼痛VAS评分与对照组相比，无统计学意义（P>0.05），观察组平均愈合时间低于对照组，差异有统计学意义（P<0.05），观察组VSS评分明显低于对照组，差异有显著统计学意义（P<0.01），观察组愈合后水疱发生率为16.7%，明显低于对照组43.3%（P<0.01）。研究过程中未发现不良反应。[结论] 生肌膏在深Ⅱ度烧伤创面愈合后期能促进坏死组织脱落，缩短愈合时间，减少换药次数，提高创面愈合质量，无明显不良反应，值得推广。

Abstract:

[Objective] To observe the clinic effects of Shengji ointment in the later stage on deep second degree burn wound healing.[Methods] The 60 patients with deep second degree burn wounds treated in our hospital from January 2016 to December 2017 were randomly divided into 2 groups by random number table method, the control group and the observation group, with 30 cases in each group. Patients in the control group were treated with sulfadiazine silver cream for 1 times every 1~2 days until the wounds healed completely. The observation group was treated with sulfadiazine silver cream on the early stage of wound healing, and the external application of Shengji ointment was applied on the 15th day after injury, and the dressing was changed 1 times every 1~2 days until the wound healed completely. Visual analogue scale (VAS) was used to evaluate the pain of the wound in the resting state,the average healing time of the 2 groups was recorded,the Vancouver scar scale (VSS) was used to evaluate the shape of the wound after healing,the incidence of blisters was recorded within 2 weeks after wound healing,the data were statistically processed. Meanwhile, adverse reactions during the study were recorded.[Results] There was no statistically difference(P>0.05) in the pain VAS score between the observation group and the control group. the average healing time of the observation group was lower than that of the control group, and the difference was statistically significant (P<0.05), the VSS score of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.01),the incidence of blisters in the observation group was 16.7%, which was significantly lower than 43.3% in the control group (P<0.01). No adverse reactions were found during the study.[Conclusion] In the later stage on deep second degree burn wound healing,Shengji ointment can promote the necrotic tissue loss, shorten the healing time, reduce the times of dressing change, improve the quality of wound healing, and has no obvious adverse reactions, it is worth popularizing.