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中药调节树突状细胞免疫功能研究进展
贾贝田1, 赵庆云1, 蔡雨孜1, 王丽2, 边育红1
1.天津中医药大学, 天津 300193;2.天津市第二人民医院, 天津 300192
摘要:
树突状细胞(DCs)是目前已知的功能最强且唯一能激活初始型T细胞、激发初次免疫应答的抗原呈递细胞,在许多免疫系统疾病的发生、发展过程中发挥极为重要的作用。近年来,关于中药对DCs免疫功能的影响越来越受重视,调节DCs免疫活性有望成为中药治疗免疫疾病的重要靶点。文章就近几年中药对DCs免疫功能的影响进行综述。
关键词:  树突状细胞  中药  免疫调节
DOI:10.11656/j.issn.1672-1519.2018.12.22
分类号:R730.52
基金项目:国家自然科学基金面上项目(81573707)。
Research progress of immunoregulatory effects of traditional Chinese medicine on dendritic cells
JIA Beitian1, ZHAO Qingyun1, CAI Yuzi1, WANG Li2, BIAN Yuhong1
1.Tianjin University of traditional Chinese Medicine, Tianjin 300193, China;2.Tianjin Second People's Hospital, Tianjin 300192, China
Abstract:
Dendritic cells (DCs) are a kind of antigen presenting cells which have been demonstrated to have significant effects including activating naive T cells and initiating primary immune response. Besides, DCs play an important role in the occurrence and progression of many immune diseases. Resent years, modulating the function of DCs is becoming a hot spot in studying the immunoregulatory effects of traditional Chinese medicine on many diseases model. The author search for literature and make a review about the immunoregulatory effects of traditional Chinese medicine based on DCs.
Key words:  dendritic cell  traditional Chinese medicine  immunoregulatory effect
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