| 摘要: |
| 香菇多糖是一种具有抑制肿瘤生长并提高免疫功能的生物调节剂，大量动物实验和临床研究报道表明其具有调节免疫功能及抑制肿瘤生长的作用。目前，香菇多糖在临床抗肿瘤方面的应用较为广泛，主要用于增强放化疗疗效、降低肿瘤治疗相关不良反应、提高免疫效应和改善患者生存质量等方面。因此，文章综述了香菇多糖活性成分在临床应用等方面的最新研究进展，为香菇多糖辅助恶性肿瘤治疗提供新的思路。 |
| 关键词: 香菇多糖 肿瘤 临床应用 肿瘤免疫 |
| DOI：10.11656/j.issn.1672-1519.2019.11.26 |
| 分类号:R730.5 |
| 基金项目:国家自然科学基金项目（81503392）。 |
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| Research progress in clinical application of lentinan anti-tumor therapy |
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ZHANG Jing, SU Chang, JIA Yingjie, LI Xiaojiang
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Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| Lentinan is a biological regulation section that inhibits tumor growth and enhancing immune function. A large number of animal experiments and clinical reports indicate that it has the function of regulating immune function and inhibiting tumor growth. Lentinan is widely used for anti-tumor adjuvant therapy,aiming to increasing the efficiency,decreasing the adverse side effects,modulating the immune responses and improving the quality of life. Therefore,this paper reviews the recent research progress of lentinan in clinical application which could provide new insights in the future study design. |
| Key words: lentinan tumor clinical application tumor immunity |
