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援药药对“制何首乌-虎杖”治疗脑小血管病的理论探析
李鑫1, 张杰2, 刘伟2, 王栋先2, 王中琳2, 韩晓慧2, 王新陆2
1.山东中医药大学附属医院, 济南 250014;2.山东中医药大学, 济南 250355
摘要:
血浊是脑小血管病发生的重要病理因素,从浊血伤髓论治脑小血管病,可以为脑小血管病临床诊疗提供新的思路。援药药对“制何首乌-虎杖”为化浊行血汤的重要组成,具有化浊益髓的作用。文章主要从脑小血管病的病因病机、治疗原则、援药药对配伍意义、援药药对的相关药理研究4个方面对援药药对“制何首乌-虎杖”治疗脑小血管病进行理论探讨。
关键词:  脑小血管病  制何首乌-虎杖  援药药对  中医理论  药理学研究
DOI:10.11656/j.issn.1672-1519.2021.05.05
分类号:R743
基金项目:山东省中医药科技发展计划项目(2017-051);山东省卫生健康委员会齐鲁内科血浊学术流派传承工作室建设项目(鲁卫函[2021]45号);泰山学者青年专家计划项目(tsqn201909186)。
Theoretical discussion on the treatment of cerebral small vessel disease by using the assistant medications pair of “Radix Polygoni Multiflori-Polygonum cuspidatum”
LI Xin1, ZHANG Jie2, LIU Wei2, WANG Dongxian2, WANG Zhonglin2, HAN Xiaohui2, WANG Xinlu2
1.Affiliated Hospital ofShandong University ofTraditional Chinese Medicine, Jinan 250014, China;2.Shandong University of Traditional Chinese Medicine, Jinan 250355, China
Abstract:
Turbidity of blood is an important pathological factor of cerebral small vessel disease. Treating cerebral small vessel diseasefrom turbid blood hurting marrow can provide new ideas for clinical diagnosis and treatment of cerebral small vessel disease. "Radix Polygoni Multiflori-Polygonum cuspidatum" is an important component of Huazhuo Xingxue Decoction,which has the function of dispelling turbidityand benefiting marrow. This article mainly discusses the treatment of cerebral small vessel disease with the assistant medications pair of"Radix Polygoni Multiflori-Polygonum cuspidatum" from four aspects:etiology and pathogenesis,treatment principle,compatibility significance andrelated pharmacological research.
Key words:  cerebral small vessel disease  Radix Polygoni Multiflori-Polygonum cuspidatum  assistant medications pair  theroy of traditional Chinese medicine  pharmacological research
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