| 摘要: |
| 中国的前列腺癌发病率不断升高，前列腺癌最终会进展成为去势抵抗性前列腺癌（CRPC）。CRPC的治疗有许多问题尚待解决。化疗药物、免疫疫苗及新型内分泌药物等在CRPC的治疗上取得了疗效证据。中医药具有整体调节、扶正祛邪的优势。近年来针对中医药治疗CRPC的病因病机、临床疗效及作用机制开展了卓有成效的研究，中医药为CRPC的临床治疗开辟了新的途径。 |
| 关键词: 去势抵抗性前列腺癌 中医治疗 发病机制 |
| DOI：10.11656/j.issn.1672-1519.2021.05.27 |
| 分类号:R737.25 |
| 基金项目:国家自然科学基金面上项目（81872078）；天津市自然科学基金面上项目（18JCYBJC26700）；天津医科大学第二医院临床研究项目（ChiCTR1900024895）。 |
|
| Clinical research progress of traditional Chinese medicine in treatment of castration resistant prostate cancer |
|
WANG Yong, WANG Chao, NIU Yuanjie
|
|
Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China
|
| Abstract: |
| The incidence of prostate cancer in China is increasing. Prostate cancer will eventually progress to castration resistant prostate cancer (CRPC). There are many problems in the treatment of CRPC that remain to be resolved. Chemotherapy drugs,immune vaccines and new endocrine drugs have obtained evidence of efficacy in the treatment of CRPC. Traditional Chinese medicine has the advantages of overall regulation,strengthening the body and eliminating evil. In recent years,fruitful researches have been carried out on the etiology,pathogenesis,clinical efficacy and mechanism of CRPC treated with traditional Chinese medicine. Traditional Chinese medicine has opened up a new way for the clinical treatment of CRPC. |
| Key words: castration resistant prostate cancer traditional Chinese medicine treatment pathogenesis |
