房颤的发病机制研究及其中西医结合治疗进展

Research on the pathogenesis of atrial fibrillation and progress in the treatment of integrated traditional Chinese and Western medicine

关键词:  房颤  氧化应激  成纤维细胞

Key words:  atrial fibrillation  oxidative stress  fibroblasts

摘要:

心房颤动（AF）是极其常见的心律失常之一，可使心脏节律发生紊乱，导致血栓形成，对人类健康造成极大危害。诸多研究表明，心脏纤维化造成的心脏结构改变和电重构，在AF的发作和持续过程中起着非常重要的作用。采用西药治疗AF常存在不良反应多的弊端，联合中医药治疗疗效更佳，可明显提高AF患者的生活质量和生存率。文章通过研究分析国内外相关文献，从西医和中医的角度对AF的发病机制与治疗进行论述。

Abstract:

Atrial fibrillation(AF) is the most common arrhythmia, which can cause heart rhythm disturbances, cause thrombosis, and cause great harm to human health. Many studies have shown that heart structure changes and electrical remodeling caused by cardiac fibrosis play a very important role in the onset and persistence of AF. Western medicine has many adverse reactions in the treatment of AF, and the combination of traditional Chinese medicine has a better effect, which can significantly improve the quality of life and survival rate of AF patients. In this paper, through research and analysis of relevant domestic and foreign literature, the pathogenesis and treatment of AF are reviewed from the perspective of Western medicine and traditional Chinese medicine.