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基于肠道菌群-肠-脑轴理论探讨腹部推拿防治广泛性焦虑症的新思路
包安1,2, 李华南1,2, 张玮1,2, 陈英英1,2, 王海腾1,2, 王金贵1
1.天津中医药大学第一附属医院, 天津 300193;2.国家中医药管理局推拿手法生物效应三级实验室, 天津 300193
摘要:
肠道菌群对于人体健康的重要作用正在被不断揭示,肠道菌群通过神经递质、免疫、内分泌、代谢产物等多种途径实现肠道与大脑间的双向互动,从而影响精神情志疾病的发生发展。广泛性焦虑症作为一种精神情志类疾病,与菌群-肠-脑轴失衡密切相关,研究证实腹部推拿、针灸等中医药治疗对广泛性焦虑症的防治具有积极作用。文章将以菌群-肠-脑轴作为切入点,探讨腹部推拿防治广泛性焦虑症的可行性,旨在为防治广泛性焦虑症提供新的思路和契机。
关键词:  腹部推拿  菌群-肠-脑轴  广泛性焦虑症
DOI:10.11656/j.issn.1672-1519.2021.12.12
分类号:R749.7
基金项目:国家自然科学基金项目(81873393、81873394);天津市卫生健康委员会、天津市中医药管理局中医、中西医结合科研课题(2019061);区域中医(推拿)诊疗中心项目(20200424);国家中医药管理局“十二五”推拿学重点学科;天津市级推拿学教学团队项目;天津市131第三层次人才建设项目。
Based on the microbiome-gut-brain axis theory to explore new ideas for abdominal massage to prevent and treat generalized anxiety disorder
BAO An1,2, LI Huanan1,2, ZHANG Wei1,2, CHEN Yingying1,2, WANG Haiteng1,2, WANG Jingui1
1.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Grade 3 Laboratory for Biological Effects of Tuina, National Administration of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:
The important role of the intestinal flora for human health is constantly being revealed. The intestinal flora achieves the mutual interaction between the intestine and the brain through neurotransmitters, immunity, endocrine, metabolites and other ways, thereby affecting mental and emotional diseases. The occurrence and development of generalized anxiety disorder, as a kind of mental and emotional disease, is closely related to the imbalance of microbiome-gut-brain axis. Studies have confirmed that traditional Chinese medicine treatments such as abdominal massage and acupuncture have a positive effect on the prevention and treatment of generalized anxiety disorder. This article will take the microbiome-gut-brain axis as an entry point to explore the feasibility of abdominal massage to prevent and treat generalized anxiety disorder, aiming to provide new ideas and opportunities for prevention and treatment of generalized anxiety disorder.
Key words:  abdominal massage  microbiome-gut-brain axis  generalized anxiety disorder
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