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| 试论肠道菌群在腹部推拿防治肠易激综合征中的作用机制 |
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吴秋君1,2,3, 李华南1,2,4, 张海宁1,2,3, 范顺1,2,3, 李进阳1,2,3, 王金贵1,2
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1.天津中医药大学第一附属医院, 天津 300193;2.国家中医针灸临床医学研究中心, 天津 300193;3.天津中医药大学研究生院, 天津 301617;4.国家中医药管理局推拿手法生物效应三级实验室, 天津 300193
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| 摘要: |
| 腹部推拿作为中医传统外治疗法之一，在治疗肠易激综合征（IBS）中具有明确疗效，但其作用机制尚不明确。肠道菌群作为近年来的热点话题，随着研究的深入，发现IBS患者均存在肠道菌群异常，且腹部推拿对其有调控作用。文章结合现有腹部推拿防治IBS的机制研究，尝试从肠道菌群角度，探讨腹部推拿干预IBS多种途径间的关键因素和各病理因素间的纽带关系，希望为今后进一步研究腹部推拿防治IBS提供新的思路。 |
| 关键词: 肠道菌群|腹部推拿|肠易激综合征 |
| DOI：10.11656/j.issn.1672-1519.2023.03.07 |
| 分类号:R574.4 |
| 基金项目:国家区域中医（推拿）诊疗中心项目；国家自然科学基金项目（81873394）；国家中医药管理局中医药传承与创新“百千万”人才工程（岐黄工程）岐黄学者（国中医药人教函〔2021〕203号）；第七批全国老中医药专家学术经验继承工作项目；天津市131优秀人才培养项目。 |
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| Mechanisms of gut microbiome in the prevention and treatment of irritable bowel syndrome by abdominal massage |
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WU Qiujun1,2,3, LI Huanan1,2,4, ZHANG Haining1,2,3, FAN Shun1,2,3, LI Jinyang1,2,3, WANG Jingui1,2
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1.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China;3.Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;4.The State Administration of Traditional Chinese Medicine Massage Biological Effect of Laboratory, Tianjin 300193, China
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| Abstract: |
| Abdominal massage,as one of the traditional Chinese external therapies,has a definite efficacy in the treatment of irritable bowel syndrome (IBS),but its mechanism of action is still unclear. The gut microbiome as a hot topic in recent years,with the progress of research,it has been found that IBS patients all have abnormal intestinal flora,and the abdominal massage has a regulatory effect on it. Combined with the existing research on the mechanism of abdominal massage preventing IBS,the artical try to explore from the perspective of the intestinal flora and explore the key factor among the multiple pathways of abdominal massage intervention in IBS and the bond relationship between each pathological factor. Through this paper,it is hoped to provide new ideas for further research on the prevention and treatment of IBS by abdominal massage in the future. |
| Key words: gut microbiome|abdominal massage|irritable bowel syndrome |
