不同干燥条件下黄芩主要成分含量及β-葡萄糖醛酸苷酶活性变化规律研究

Research on changes of main compounds' contents and activity of β-glucuronidase in different drying conditions of radix scutellariae

关键词:  黄芩  干燥方式  β-葡萄糖醛酸苷酶  产地加工

Key words:  radix scutellariae  drying method  β-glucuronidase  habitat processing

摘要:

[目的] 揭示黄芩药材在不同干燥条件下主要成分及β-葡萄糖醛酸苷酶活性的变化规律，探究黄芩药材产地加工的适宜方法。[方法] 制备不同干燥条件下的黄芩药材样品，研究干燥过程中黄芩药材样品的失水率、主要成分的含量及β-葡萄糖醛酸苷酶活性。[结果] 不同干燥条件下黄芩药材中主要指标成分含量基本一致，黄芩苷含量均符合2020年版《中国药典》规定；随着干燥温度升高，药材中β-葡萄糖醛酸苷酶活性明显降低。[结论] 不同干燥方式对黄芩主要成分含量影响较小，温度升高有效灭活黄芩药材中的β-葡萄糖醛酸苷酶，为黄芩产地加工提供了参考。

Abstract:

[Objective] To insight into the changes of the main compounds' contents and β-glucuronidase activity of radix scutellariae under different drying conditions so as to investigate a suitable method for the habitat processing.[Methods] Samples of radix scutellariae by different drying methods were prepared, whose water loss rate, contents of main compounds and activity of β-glucuronidase were researched during the drying process.[Results] The contents of main index compounds in radix scutellariae under different drying conditions were basically consistent. Baicalin content satisfied the standard in the 2020 edition of the Chinese Pharmacopoeia. Besides, the β-glucuronidase activity of radix scutellariae decreased significantly with the increase of the processed temperature.[Conclusion] The effect of different drying methods on the contents of main ingredients in radix scutellariae is relatively negligible, while the elevated temperature can effectively inactivate the β-glucuronidase in radix scutellariae. Overall, this study provides guidance and reference for the habitat processing of radix scutellariae.