基于“补肾活血、降浊排毒法”的CRF疾病管理方案研究

Research on CRF disease management program based on “tonifying kidney and promoting blood circulation，lowering turbidity and detoxification”

关键词:  慢性肾衰  疾病管理方案  补肾活血降浊排毒

Key words:  chronic renal failure  disease management program  tonifying kidney activating blood lowering turbidity and detoxifying

摘要:

[目的] 旨在观察应用“补肾活血、降浊排毒法”的慢性肾功能衰竭（CRF）疾病管理方案，对CRF患者的治疗效果及临床症状改善情况进行分析。[方法] 纳入2019—2021年门诊及住院CRF患者，选取该院收治的237例CRF患者，将入组者随机分为观察组和对照组，观察组137例，对照组100例，对照组进行常规治疗，观察组在对照组基础上采用“补肾活血、降浊排毒法”的CRF疾病管理方案，比较分析两组患者尿素氮、肌酐、尿酸、肾小球滤过率、内生肌酐清除率等临床指标和症状积分在治疗前后的变化。[结果] 观察组的症状积分方面总有效率达64.23%，高于对照组的39%（P＜0.05）；同时，观察组在实验室指标和症状积分方面与对照组比较均有改善（P＜0.05）。[结论] “补肾活血、降浊排毒法”的CRF疾病管理方案可改善患者临床症状，除了能有效改善肾功能等相关临床指标外，还能缓解患者临床症状和体征，改善患者的就医体验，为慢性肾脏病管理提供了新思路和新方法。

Abstract:

[Objective] To observe the CRF disease management program of “tonifying kidney and promoting blood circulation，reducing turbidity and detoxification” and analyze the therapeutic effect and improvement of clinical symptoms in patients with chronic renal failure. [Methods] The 237 patients with chronic renal failure admitted to the hospital from 2019 to 2021 were included in this study. The enrolled patients were randomly divided into observation group and control group，137 patients in observation group and 100 patients in control group，and the control group was received routine treatment. On the basis of the control group，the observation group was given the CRF disease management program which is “tonifying kidney and promoting blood circulation，reducing turbidity and detoxifying”，and the changes of urea nitrogen，creatinine，uric acid，glomerular filtration rate，endogenous creatinine clearance and other clinical indexes and symptom scores before and after treatment were compared between the two groups. [Results] The total effective rate of the observation group was 64.23%，which was higher than that of the control group（39%，P＜0.05）. At the same time，the laboratory indexes and symptom scores were improved in the observation group compared with the control group（P＜0.05）. [Conclusion] The CRF disease management program of “tonifying kidney and promoting blood circulation，reducing turbidity and detoxification” can improve patients’ clinical symptoms. In addition to effectively improving kidney function and other related clinical indicators，it can also relieve patients’ clinical symptoms and signs，improve patients’ medical experience，and provide a new idea and a new method for the management of chronic kidney disease.