| 摘要: |
| 质谱仪是由离子源、质量分析器和离子检测器组成的仪器统称，其最初用于对同位素的分离和检测。近年来在中药研究领域得到了一定程度的应用，并取得了较好的研究成果。文章就质谱仪的种类及特点、质谱仪与其他仪器联用及优势、质谱仪在中药研究领域的应用等内容进行了综述，为更好地使用质谱仪及进行中药研究与分析提供参考。 |
| 关键词: 质谱仪 中药 化学成分鉴定 代谢分析 质量控制 |
| DOI：10.11656/j.issn.1672-1519.2024.08.20 |
| 分类号:R914.1 |
| 基金项目:中国工程院战略研究与咨询项目(2022-XBZD-15);国家自然科学基金委专项(L2124006)。 |
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| Application status and trend of mass spectrometer in traditional Chinese medicine research |
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CHEN Hongrui1, CHEN Yibing2, XIE Tian2, XUE Xiaojuan2
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1.Center for Clinical Pharmacology, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China;2.Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
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| Abstract: |
| A mass spectrometer is an instrument used for separating and detecting different isotopes. In recent years，it has been applied to a certain extent in the field of traditional Chinese medicine research and has yielded favorable research outcomes. This article provides a comprehensive review of the synergies and advantages of combining mass spectrometers with other instruments，as well as the application of mass spectrometers in traditional Chinese medicine research. This research intends to serve as a reference source for better utilizing mass spectrometers and conducting research and analysis in the field of traditional Chinese medicine. |
| Key words: mass spectrometers traditional Chinese medicine identification of chemical components metabolite analysis quality control |
