| 摘要: |
| 目的: 研究柏子仁单方对猫觉醒——睡眠节律的影响.方法:采用多导睡眠图描记方法,以脑电图(EEG)、肌电图(EMG)、(EDG)不同变化为睡眠分期的区分指标.结果: 腹腔注射柏子仁单方注射液后,睡眠时间在注射药物后第2个小时段即延长,并缓慢增加,第6个小时段增加达最大,之后缓慢降低.猫在睡眠过程中,与对照实验组相比,慢波睡眠期延长(P<0.001),其中慢波睡眠浅睡期延长(P<0.05),慢波睡眠深睡期明显延长(P<0.001);异相睡眠期变化无统计学意义.结论: 柏子仁醇法提取后的有效成分可使猫的慢波睡眠时间延长,提示其有效成分有助于猫的入睡,并使深睡时间明显延长,对体力恢复作用很显著. |
| 关键词: 猫 多导睡眠图 柏子仁 |
| DOI：10.11656/j.issn.1673-9043.2000.03.28 |
| 分类号: |
| 基金项目:武警医学院院级课题 |
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| Effect of Semen Biotae on Polysomnography in cat |
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Li Haisheng, Wang Anlin, Yu Liren
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Departm ent of physiology,Medical College of the Chinese People's Armed Police Forces,Tianjin 300162
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| Abstract: |
| To investigate the Semen Biotae's effects on Sleep-Wakefuluess regulation.Method: We used Polysom nography to record the change of EEG,EMG and EOG in different sleep periods,and observed the influence of Se-men Biotae in 6 mature cat (frmale or male,weight betwnne 2.7-3.4kg)1.Operation and record methods-often one week of laying electrodes into the the cathead,We began to test.During experiment,we put the cat into the the shielded box,and use RM-6000 eight-channel polygraph record system to measure the change of the cat'ECG,EMG and EOG.2.Drug ad-ministration-raw extraction of Semen Biotae (lg/ml),contrast (ethanol and 0.9%NaCl,1:9),were injected into the cat'abdominal cavity.The experiment interval is 3days.3.Statistical analyses-pairedt-test was used.Significance level chosen was p value less than 0.05(P<0.05) and all tests were two-sided.Results: After single use of Semen Biotae injection,often 2 hours of injection,the sleep time enlonged,increased slowly and reached the climax in the 4th hour,then slow down.the cat's SWS enlonged:SWS Ⅰ enlonged and SWS Ⅱ enlonged significant.PS changes had no significant difference.Conclusion: In this experiment,the ethanol extraction of Semen Biotae can help the cat sleep deeply.Through this research,we analysed the mechanism of the drug'effect to "XIN JI SHI MIAN,JING JI ZHENG ZHONG" using modern techniques. |
| Key words: Cat Polysomnography Semen Biotae |
