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补肾调冲方改善促排卵周期中子宫内膜容受性的临床观察*
王利红1, 赵丽颖2, 夏天3
1.山东中医药大学附属医院中西医结合生殖与遗传中心 250011;2.天津中医药大学 300193;3.天津中医药大学第一附属医院 300193
摘要:
[目的]探讨补肾调冲方对不孕症患者促排卵周期子宫内膜容受性的影响。[方法]将36例子宫内膜生长不良继发不孕患者随机分为中药组及戊酸雌二醇对照组,应用经阴道彩色多普勒超声检测绒毛促性腺激素(HCG)注射日子宫内膜厚度、类型及血流状态。[结果]1)中药组子宫内膜厚度较对照组明显改善,差异显著(P<0.05)。2)中药组A型+B型内膜与对照组比较差异无统计学意义(P>0.05)。3)中药组子宫内膜阻力指数(RI)和搏动指数(PI)明显低于对照组,差异有统计学意义(P<0.01);子宫内膜穿支血流与对照组比较,差异有统计学意义(P<0.05)。4)中药组临床妊娠率高于对照组,差异有统计学意义(P<0.05)。[结论]补肾调冲方有增加子宫内膜厚度及改善子宫内膜血流的作用,可提高子宫内膜容受性,有助于胚胎着床。
关键词:  子宫内膜容受性  补肾调冲方  不孕症
DOI:10.11656/j.issn.1673-9043.2011.03.10
分类号:
基金项目:* 国家自然科学基金面上项目(30801479)
Clinical observation on improving endometrial receptivity of Bushen Tiaochong prescription during ovulation cycle
WANG Li-hong1, ZHAO Li-ying2, XIA Tian3
1.Reproductive and Genetic Center, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, China;2.Tianjin Universty of TCM, Tianjin 300193, China;3.The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China
Abstract:
[Objective] To discuss the effect of Bushen Tiaochong prescription on the improvement of endometrial receptivity in patients with infertility during ovulation cycle.[Methods] The 36 infertile women due to poor endometrial development were randomly divided into two groups:traditional Chinese medicine group and control group treated with estradiol valerate.Transvaginal color Doppler flow imaging was employed to measure the endometrium thickness,type and bloodstream condition of the two groups in the day of injection of human chorionic gonadotropin (HCG).[Results]1) The endometrium thickness in the traditional Chinese medicine group was obviously improved compared with that in the control group with a significant difference (P<0.05).2) A+B type of endometrium in traditional Chinese medicine group had no significant difference compared with that in the control group (P>0.05).3) The resistance index (RI) and pulsate index (PI) of the endometrium in traditional Chinese medicine group was obviously lower than that in the control group with a significant difference between these two groups (P<0.01).The communicating artery of the endometrium in traditional Chinese medicine group compared with the control group showed a significant difference (P<0.05).4) The pregnancy rate in the traditional Chinese medicine group was significantly higher than that in the control group with a significant difference (P<0.05).[Conclusion] It is suggested that Bushen Tiaochong prescription can increase endometrium thickness,improve bloodstream condition and endometrial receptivity helped
Key words:  endometrial receptivity  Bushen Tiaochong prescription  infertility
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