参附注射液治疗休克的临床研究*

Clinical study on effect of Shenfu injection in treating shock

关键词:  参附注射液  休克  临床研究

Key words:  Shenfu injection  shock  clinical study

摘要:

[目的]观察参附注射液对休克的治疗作用。[方法]采用自身前后对照的研究方法对66例休克患者随机分成对照组和治疗组。对照组给予常规治疗,治疗组在常规治疗基础上加用参附注射液100 mL静脉注射。[结果]两组治疗后各时点与治疗前比较收缩压(SBP)、舒张压(DBP)、每分钟输出量(CO)升高(P<0.05),心率(HR)下降(P<0.05)且治疗组变化更快、更明显,两组比较差异有统计学意义。治疗组患者尿量明显多于对照组,同时输液量及多巴胺使用量均少于对照组,两组比较差异有统计学意义。[结论]参附注射液可迅速恢复休克患者血流动力学稳定。

Abstract:

[Objective] To study the therapeutic effect of Shenfu injection on shock.[Methods] Self-control method was used.Sixty-six patients with shock were randomly divided into control group and treatment group.The control group was given routine treatment,and the treatment group was given routine treatment combined with 100 mL intravenous Shenfu injection.[Results] Compared with the results before treatment,SBP,DBP,CO at each time point after treatment of two groups were significantly increased (P<0.05),but HR was significantly decreased (P<0.05).More faster and obvious change was observed in the treatment group.The urine output of the patients in the treatment group was significantly more than that in the treatment group.At the same time,the volume of transfusion and the usage of dopamine was less than that in the treatment group with significant difference between these two groups.[Conclusion] Shenfu injection can restore the stability of hemodynamics quickly.