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菟丝子、骨碎补提取物体外对酪氨酸酶活性的影响
杜娟, 夏佳楠, 沈丽, 王元元, 王亚苹, 张德芹
300193 天津中医药大学
摘要:
[目的] 考察菟丝子、骨碎补提取物体外对酪氨酸酶活性的影响。[方法] 采用蘑菇酪氨酸酶多巴速率氧化法检测菟丝子、骨碎补对酪氨酸酶的激活率。[结果] 菟丝子、骨碎补提取物对酪氨酸酶活性具有激活作用。[结论] 菟丝子、骨碎补提取物能够激活酪氨酸酶活性,为其外用治疗白癜风提供了药学依据。
关键词:  菟丝子提取物  骨碎补提取物  酪氨酸酶活性
DOI:10.11656/j.issn.1673-9043.2013.01.16
分类号:
基金项目:国家科技支撑计划资助项目(2008BA153B09).
External effect of extract of Cuscutae semen and Drynaria fortunei on activity of tyrosinase
DU Juan, XIA Jia-nan, SHEN Li, WANG Yuan-yuan, WANG Ya-ping, ZHANG De-qin
Tianjin University of TCM, Tianjin 300193, China
Abstract:
[Objective] To evaluate the external effect of the extract of Cuscutae Semen and Drynaria fortunei on the activity of tyrosinase. [Methods] Experiments in vitro were performed to evaluate the effects of the extracts from the Cuscutae Semen and Drynaria fortunei on the activity of tyrosinase. [Results] The results showed that the extract of Cuscutae Semen and Drynaria fortunei could activate tyrosinase. [Conclusion] The effectiveness of the extract of Cuscutae Semen and Drynaria fortunei for the activity of tyrosinase provide basis of pharmacodynamics for treating vitiligo.
Key words:  Cuscutae Semen extract  Drynaria fortunei  the activity of tyrosinase
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