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不同厂家D101大孔树脂对赤芍提取物纯化工艺考察
李雪茹, 刘虹, 姜佳, 郝彧, 张德芹
天津中医药大学中医药研究院, 教育部方剂学重点实验室, 天津 300193
摘要:
[目的] 考察相同型号(D101)不同厂家生产的大孔吸附树脂对芍药苷的富集工艺比较. [方法] 以芍药苷为指标,对树脂的静态和动态吸附、解吸附性能进行了考察. [结果] A、B两个厂家静态吸附和解吸附性能较好,而B、D、E 3个厂家的动态吸附和解吸附性能较好. [结论] 不同厂家生产的D101大孔树脂在对芍药苷的吸附和解吸附性能上存在一定的差异.
关键词:  赤芍  芍药苷  D101大孔树脂
DOI:10.11656/j.issn.1673-9043.2014.01.17
分类号:
基金项目:“重大新药创制”科技重大专项基金项目(2012ZX 09101212).
Study on effect of D101 macroporous resin produced by different manufacturers in Paeoniae extract purification
LI Xue-ru, LIU Hong, JIANG Jia, HAO Yu, ZHANG De-qin
Institute of Traditional Chinese Medcine, Tianjin University of TCM, Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin 300193, China
Abstract:
[Objective] To perform a comparative study about the same type of macroporous resins from different manufactures on peoniflorin enriching. [Methods] Peoniflorin was taken as the index to investigate the resins' static and dynamic absorbtion and desorption performance.[Results] D101 macroporous resin from A and B manufactures had a high static absorbtion and desorption performance, but B, D and E had a high performance in dynamic absorption and desorption.[Conclusion] There are some differences on the enrichment of peoniflorin by the same type of macroporous resins from different manufactures.
Key words:  Radix paeoniae rubra  Peoniflorin  D101 macroporous resin
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