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丹参促创伤修复机制的研究进展
张泽曦, 夏庆梅, 刘洋, 张萌, 郭虹, 张晗
天津中医药大学, 天津 300193
摘要:
通过大量临床实践证明,丹参是皮肤愈合,创伤修复的良药.随着丹参的运用范围不断扩大,人们对其作用机制,特别是对其促进创伤修复的机制有了更深入广泛的研究.现将近年来国内外学者对丹参及其药理活性成分关于促进创伤组织修复机制的研究进展,从促进微循环、免疫调节作用、抑制过再生、减轻组织缺血- 再灌注损伤、促进创伤组织再生、抑制炎症反应及细胞凋亡及其与生长因子的关系等方面进行综述.
关键词:  丹参  创伤修复机制  研究进展
DOI:10.11656/j.issn.1673-9043.2015.01.15
分类号:
基金项目:大学生科技创新基金(CXJJ2012C02);教育部科学技术重点研究项目(212006);国家自然科学基金(8137 3789).
Research progress of the mechanism about Salvia Miltiorrhiza promoting wound repair
ZHANG Ze-xi, XIA Qing-mei, LIU Yang, ZHANG Meng, GUO Hong, ZHANG Han
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Abstract:
In recent years, through a large number of clinical practice has proved that Salvia Miltiorrhiza is the medicine of the skin healing, wound healing, and to promote wound healing. With the application range of Salvia Miltiorrhiza expanding, promote wound healing mechanism has a more in-depth study. The author summarize the scholars at domestic and foreign in recent ten years in Salvia Militiorrhiza and its pharmacological active ingredients promote wound tissue repair mechanism research progress, from promote microcirculation, immune regulation, inhibiting regeneration, reduce tissue ischemia-reperfusion injury and promote wound tissue regeneration, inhibiting inflammatory reaction and apoptosis and its relationship with growth factors and other aspects as follows.
Key words:  Salvia Miltiorrhiza  wound healing  research progress
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