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中医五行学说的分子生克机制初探
孙雷, 彭欣, 秦林
山东中医药大学基础医学院, 山东省济南市长清区大学科技园, 济南 250355
摘要:
现代生物学的理论与方法日益为传统中医学研究所用。探讨中医五行学说中生物大分子五行生克机制, 揭示生物大分子与机体脏腑组织器官之间的内在联系, 可为指导临床诊断与治疗提供一定的理论依据。通过运用中医五行原理, 结合分子生物学的中心法则和生化的分子代谢原理, 并结合国内外最新研究成果, 初步发现生物大分子的中医五行配属为DNA属肾水, RNA与肝木相配, 蛋白质配心火, 糖类为脾土, 脂类属肺金。大分子之间不仅存在已知的DNA衍生RNA、RNA衍生蛋白质、蛋白质衍生糖和糖衍生脂类之直线关系, 而且存在着与机体五行五脏相关的"相生、相克"之循环关系。
关键词:  中医五行  生物大分子  关系  相生  相克
DOI:10.11656/j.issn.1673-9043.2014.02
分类号:
基金项目:山东省自然科学基金资助课题(ZR2013HM053).
Molecular connotation of Chinese medicine Wuxing theory
SUN Lei, PENG Xin, QIN Lin
College of Basic Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
Abstract:
The modern biological theories and methods have been introduced to study traditional Chinese medicine. Exploring the biological molecular generation/inhibition mechanism of traditional Chinese medicine (TCM) Wuxing theory and discovering the connection between biological molecules and the Zangfu in terms of TCM would implement the TCM theory concerning diagnosis and treatment. On the ground of TCM Wuxing theory, the central dogma and biochemical metabolism, as well as the latest progress, we proposed that the Wuxing traits apply to biological molecules, that is, DNA represents for Shen-shui, RNA for Gan-mu, protein for Xin-huo, sugar for Pi-tu and lipid for Fei-jin, and that in addition to the linear relationship that RNA is derived from DNA, protein from RNA, protein from RNA, sugar from protein and lipid from sugar, the molecular circle of generation/inhibition exists, similar to Chinese medicine Wuxing theory.
Key words:  Chinese medicine Wuxing theory  biological molecule  relationship  generation  inhibition
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