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| 细胞膜色谱法在中药活性成分筛选中的应用 |
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武姿彤1, 杜武勋2, 肖学凤1, 徐亮3, 张富赓4, 张瑜1
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1.天津中医药大学, 天津 300193;2.天津中医药大学第二附属医院, 天津 300150;3.天津医科大学, 天津 300070;4.天津市环湖医院, 天津 300060
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| 摘要: |
| 细胞膜色谱法是近年来应用于中药研究的生物色谱技术。现对细胞膜色谱法的原理、特性及已用于中药研究的不同细胞膜类型进行简要概括，并对中药单体及中药复方活性成分筛选中的典型应用进行了综述。同时就细胞膜色谱法在中药活性成分筛选中存在的问题和其应用中存在的局限性提出了建议和设想，为今后更好的将细胞膜色谱法应用于中药研究提供参考。 |
| 关键词: 细胞膜色谱法 中药 活性成分 筛选 |
| DOI：10.11656/j.issn.1673-9043.2017.01.18 |
| 分类号: |
| 基金项目:天津市中医药管理局中医、中西医结合科研专项基金项目（2015050）。 |
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| Advances in application of cell membrane chromatography in screening bioactive components of traditional Chinese medicines |
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WU Zi-tong1, DU Wu-xun2, XIAO Xue-feng1, XU Liang3, ZHANG Fu-geng4, ZHANG Yu1
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1.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China;3.Tianjin Medical University, Tianjin 300070, China;4.Tianjin Huanhu Hospital, Tianjin 300060, China
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| Abstract: |
| Cell membrane chromatography is a biochromatography technology used in traditional Chinese medicines(TCMs) in recent years. The principles, characteristics and different cell membrane types were summarized in this review. The typical application in screening bioactive components of TCMs were also summarized. At the same time,the possible problems and limitations faced when working with TCMs were discussed, providing references to cell membrane chromatography for better apply to TCMs. |
| Key words: cell membrane chromatography traditional Chinese medicines bioactive components screening |
