| 摘要: |
| 伏邪理论来源于《黄帝内经》，至今仍在中医学病因理论中占重要部分，卵巢癌在妇科肿瘤中恶性度最高，早期难以发觉，治疗难度大。文章以伏邪理论探讨卵巢癌的发病机制，认为患者因内属先天伏寒体质，外受淫邪，化为伏毒而发病，与西医遗传因素中BRCA1/2基因突变的影响具有相关性，为中医学预防及改善卵巢癌患者状态提供思路。 |
| 关键词: 卵巢癌 伏邪 先天伏寒证 伏毒 BRCA1/2基因突变 |
| DOI：10.11656/j.issn.1673-9043.2019.05.04 |
| 分类号:R737.31 |
| 基金项目:国家自然科学基金项目（81473717）。 |
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| Incubated Pathogenic Theory and BRCA1/2 Mutations: discussion on the pathogenesis of ovarian cancer from perspective of integrated traditional Chinese medicine and western medicine |
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XIAO Qiao,SHEN Ying,HAN Fengjuan
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1.Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China;2.Heilongjiang University of Chinese Medicine, Harbin 150040, China
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| Abstract: |
| Incubated pathogenic theory,which derives from Yellow Emperor's Inner Canon,is a significant part of etiology theory in TCM. Ovarian cancer is the most lethal gynecological tumors for its difficult to early detect and treatment. The article explores ovarian cancer' etiology with incubated pathogenic theory,and believes that the origin cause of ovarian cancer from TCM's view is congenital latent cold syndrome and latent toxicity factor,which in WM's point links to BRCA1/2 mutations,it provides ideas for the prevention and improvement in ovarian cancer with traditional Chinese medicine. |
| Key words: ovarian cancer incubated pathogenic theory congenital latent cold syndrome latent toxicity BRCA1/2 mutations |
