虫类药物“虫蚁搜剔”改善骨髓微环境的理论探讨

Theoretical discussion on the improvement of the bone marrow microenvironment by the “insects and ants scavenging” of insect medicine

关键词:  骨髓微环境  虫蚁搜剔  瘀毒入络  虫类复方药物

Key words:  bone marrow microenvironment  insects and ants scavenging  stasis toxin enters the network  insect compound medicine

摘要:

骨髓微环境是造血干细胞生长发育的场所，在血液系统疾病中，骨髓微环境的稳态对于疾病的预后具有重要意义。血液病的临床治疗中，靶向药、免疫调节类药物及骨髓移植等技术不断发展，精准治疗的背后，是否有药物能配合改善骨髓微环境进而提高疗效，是一个值得研究的方向。虫类药“虫蚁搜剔”专能疗“久病入络”之疾。血液系统疾病中骨髓微环境的异常亦是“病在络”的体现。基于此，本文结合中医理论、临床及实验相关研究成果探讨虫类药“虫蚁搜剔”改善骨髓微环境的理论依据，以期为未来的研究方向开拓思路。

Abstract:

The bone marrow microenvironment is the place where hematopoietic stem cells grow and develop. In blood system diseases,the homeostasis of the bone marrow microenvironment is of great significance to the prognosis of the disease. In the clinical treatment of blood diseases,technologies such as targeted drugs,immunomodulatory drugs,and bone marrow transplantation continue to develop. Behind precision treatment,whether there are drugs that can improve the bone marrow microenvironment and improve the efficacy is a direction worth studying. The "insects and antsscavenging"of insect medicinecan cure the disease of "long-term sickness into the network". The abnormality of the bone marrow microenvironment in blood system diseases is also a manifestation of "the disease is in the network". Based on this,this article combines the theory of traditional Chinese medicine,clinical and experimental research results to explore the theoretical basis for the insect medicine "insects and ants scavenging"to improve the bone marrow microenvironment,hoping to open up ideas for future research directions.