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| Effect of Semen Biotae on Polysomnography in cat |
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| DOI
10.11656/j.issn.1673-9043.2000.03.28 |
| Key Words
Cat;Polysomnography Semen;Biotae |
| Author Name | Affiliation | | Li Haisheng | Departm ent of physiology,Medical College of the Chinese People's Armed Police Forces,Tianjin 300162 | | Wang Anlin | Departm ent of physiology,Medical College of the Chinese People's Armed Police Forces,Tianjin 300162 | | Yu Liren | Departm ent of physiology,Medical College of the Chinese People's Armed Police Forces,Tianjin 300162 |
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| Abstract
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| To investigate the Semen Biotae's effects on Sleep-Wakefuluess regulation.Method: We used Polysom nography to record the change of EEG,EMG and EOG in different sleep periods,and observed the influence of Se-men Biotae in 6 mature cat (frmale or male,weight betwnne 2.7-3.4kg)1.Operation and record methods-often one week of laying electrodes into the the cathead,We began to test.During experiment,we put the cat into the the shielded box,and use RM-6000 eight-channel polygraph record system to measure the change of the cat'ECG,EMG and EOG.2.Drug ad-ministration-raw extraction of Semen Biotae (lg/ml),contrast (ethanol and 0.9%NaCl,1:9),were injected into the cat'abdominal cavity.The experiment interval is 3days.3.Statistical analyses-pairedt-test was used.Significance level chosen was p value less than 0.05(P<0.05) and all tests were two-sided.Results: After single use of Semen Biotae injection,often 2 hours of injection,the sleep time enlonged,increased slowly and reached the climax in the 4th hour,then slow down.the cat's SWS enlonged:SWS Ⅰ enlonged and SWS Ⅱ enlonged significant.PS changes had no significant difference.Conclusion: In this experiment,the ethanol extraction of Semen Biotae can help the cat sleep deeply.Through this research,we analysed the mechanism of the drug'effect to "XIN JI SHI MIAN,JING JI ZHENG ZHONG" using modern techniques. |
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