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| Experimental research of Tiaogan Daozhuo Decoction on lipid metabolism and anti-oxidation injury |
| Hits 1516 Download times 1619 Received:July 04, 2003 |
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| DOI
10.11656/j.issn.1673-9043.2003.03.06 |
| Key Words
Tiaogan Daozhuo (regulating the liver and removing the turbid);atherosclerosis (AS);lipid;liver;malondialdchydc(MDA);supcroxidc dismutasc (SOD) |
| Author Name | Affiliation | | LI Guang-bin | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | JIANG Xi-juan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | FAN Ying-chang | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] To investigate the influence of Chinese medicine Tiaogan Daozhuo Decoction on lipid metabolism and anti-oxidation injury in rabbits with Atherosclerosis (AS) and the mechanisms of anti-AS.[Methods] The rabbits were fed with cholesterol-rich diet and underwent different management in each group simultaneously The content of total cholesterol (TC), triglyceride (TG), and malondiaLdchyde(MDA) and the activity of superoxide dismutase (SOD) in the liver were detected at the end of experiment.[Result] The content of TC, TG, MDA in model group was enhanced and the activity of SOD was decreased markedly. Tiaogan Daozhuo Decoction could inhibit the changes effectively.[Conclusion] Tiaogan Daozhuo Decoction can prevent the formation and progress of AS by inhibiting the high content of lipid and oxidation injury induced by cholesterol-rich diet. |
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